Diabetes mellitus is one of the most common endocrine disorders that affect the body’s ability to make or use insulin. Diabetes mellitus (DM), or simply diabetes, is a group of chronic metabolic diseases in which a person experience high blood sugar, either because the pancreas does not produce enough insulin or because the body cells do not effectively use or respond to the insulin that is produced. This high blood sugar produces the classical symptoms of polyuria (frequent urination), polydipsia (increased thirst) and polyphagia (increased hunger). Conventionally, diabetes has been divided into three types namely: Type 1 DM or insulin-dependent diabetes mellitus (IDDM) in which body fails to produce insulin, and presently requires the person to inject insulin or wear an insulin pump. This is also termed as "juvenile diabetes". Type 2 DM or non-insulin-dependent diabetes mellitus (NIDDM), results from insulin resistance, a condition in which cells fail to use insulin properly, with or without an absolute insulin deficiency. This type was previously referred to as or "adult-onset diabetes". The third main type is gestational diabetes which occurs when women without a previous history of diabetes develop a high blood glucose level during her pregnancy and may metamorphose to type 2 DM after giving birth. Currently available pharmacotherapy for the treatment of diabetes mellitus includes insulin and oral hypoglycemic agents. Thus, the present review underscores the issues surrounding the symptoms, diagnosis and treatment (especially use of anti-diabetic herbal species) of this killer disease with a view to suppressing its global spread and resurgence.
Results: 28(22.05%) of the 127 patients studied developed surgical site infections, based on clinical criteria and 25(19.6%) based on bacteriological criteria. Pseudomonas spp. was the most frequently cultured aerobic organism in 39% (n=11 ) of the cultures, while Klebsiella in 21% (n=6) and Staphylococcus in 17% (n=5).Over 80% of the organisms demonstrated less than 50% sensitivity to the tested antibiotics.
Conclusion:
The dreadful nature of hepatitis-B virus (HBV) and HIV infections and their common mode of transmission during pregnancy have made them become an important global health problem and a leading cause of maternal complications and neonatal deaths in both developed and developing countries. The current study determined the seroprevalence of HBV and HIV amongst pregnant women receiving antenatal care services in Kano state. Structured questionnaires were distributed to 276 (14-49 years) consenting pregnant women across the six selected health facilities to obtain demographic and socio-economic data. Three (3) ml of venous blood sample were drawn by venipuncture and centrifuged at 3000 rpm for 5 min. The serum was tested for the presence of HIV antibodies using the Abbott Determine HIV 1/2 test kit and HBV antibodies using a rapid diagnostic test kit (DiaSpot Diagnostics, USA). The \chi2 test for independence was determined using GraphPad InStat software (version 3.0). Sociodemographic characteristics of the respondents showed 95.7% of the respondents as being married, 64.5% lived in a monogamous family, 62.4% petty traders, 26.8% unemployed, 57.4% of them are 21 – 30 years of age, 41.3% have Quranic education, 28.3% are 1st gravida while 36.9% have more than 4 children. Additionally, 1.4% of HIV and 8% of HBV cases were confirmed. The chi-squared test for independence (\chi2=13.078, P=0.0003) showed a significant relationship between the two variables. HIV and HBV infections existed in the study group. Regular screening, awareness, and health education programs on the mode of their transmission should be directed to pregnant women to prevent vertical transmission.
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