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Background
Wolff‐Parkinson‐White (WPW) syndrome is one of the most common congenital cardiac abnormalities among ventricular pre‐excitation syndromes. Radiofrequency catheter ablation (RFCA) treatment of accessory pathways (APs) in WPW patients is an established curative therapy restoring normal atrioventricular conduction. We have not encountered any studies evaluating both the LA and LV functions of these patients before and after RFCA with three dimensional‐speckle tracking echocardiography (3D‐speckle tracking echocardiography (STE)).
Aim
The purpose of the current study was to assess the LA and LV functions in patients with WPW syndrome before and after RFCA using 3D‐STE.
Methods
A total of 21 patients with WPW syndrome who had been scheduled for RFCA were prospectively recruited for this study. 3D‐STE examinations of the patients were performed 12–24 h before ablation and 1 month after ablation.
Results
The LV‐global longitudinal strain (LV‐GLS) and LV‐global circumferential strain (LV‐GCS) were significantly depressed in the pre‐RFCA WPW group than in the control group (−14.3 ± 2.1 vs. −21.5 ± 2.2, p < .001; −12.6 ± 1.8 vs. −20.4 ± 1.8, p < .001, respectively). The left atrial strain‐reservoir (LAS‐r) and LAS‐active were significantly decreased in the pre‐RFCA WPW group than in the control group (31.9 ± 2.4 vs. 48.8 ± 2.6, p < .001; 11.7 ± 2 vs. 26.5 ± 2.1, p < .001, respectively). The LV‐GLS, LV‐GCS, LAS‐r, and LAS‐active values improved after RFCA compared to before.
Conclusion
The results of our study indicated that there are subclinical impairments in LV and LA myocardial dynamics in the apparently healthy WPW patients, and these deteriorations improve after RFCA of AP.
Objectives
Left ventricular thrombus is regarded as one of the main myocardial infarction complications. Knowing the left ventricular thrombus symptoms prevents serious complications that may occur. This study aims to reveal any association between SCUBE-1 and left ventricular thrombus, thought to be involved in platelet aggregation and adhesion.
Methods
The study included 80 patients diagnosed with heart failure following acute myocardial infarction, applying for the cardiology outpatient clinic for third-month follow-up. The patients were included in two groups to see if the left ventricular thrombus was present. Thus, 22 patients were found to have left ventricular thrombus. The two groups were compared based on clinical laboratory and echocardiographic parameters.
Results
It was found that the patients with left ventricular thrombus had significantly higher Serum SCUBE-1 levels (p<0.001). The optimal cutoff point of SCUBE-1 levels for predicting the LVT was >35.1 ms, with the specificity of 86% and sensitivity of 68.4% (AUC=0.815; 95% CI, 0.699–0.931; p<0.0001). SCUBE -1 level (OR=1.090, 95% CI: 1.034–1.150, p<0.001) in the multiple logistic regression model continue to significantly predict LVT after adjusting for the confounding variables, as statistically significant in the univariate analysis of the variables which correlated with the SCUBE-1 levels.
Conclusions
SCUBE-1 level was determined to independently predict the left ventricular thrombus after a previous anterior myocardial infarction.
Objectives:The aim of this study is to investigate the relationship between the GENSINI score used to show the prevalence of atherosclerotic disease in patients with acute coronary syndrome (ACS) and the red blood cell distribution volume.Material and Methods: 359 patients with a diagnosis of ACS who underwent coronary angiography were included in the study. The patients were divided into two groups as GENSINI score <20 and ≥20, by analysing their angiographic images. The demographic, clinical and laboratory parameters of these two groups were compared and the values predicting the GENISI score high were investigated.
Results:Of the 359 patients included in the study, 104 female patients were 255 men. While the number of patients with a GENSINI score of <20 was 69, the number of patients with a GENSINI score of ≥20 was 290. It was observed that Red Cell Distribution Width (RDW) value was higher in the group with GENSINI score> 20 (13.7±0.9 and 14.2±1.4 p=0.001). In the correlation analysis, a positive correlation was observed between RDW and GENSINI score (r: 0.137; p=0.009). RDW was seen to be the independent predictor of the GENSINI score. (OR: 1.417, 95% CI (1.037-1.935); p=0.029) Conclusions: RDW, which is an easy and accessible parameter in patients presenting with ACS, correlates with the severity of atherosclerotic heart disease and can be used as a predictor of atherosclerotic heart disease.
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