In the present study, the insecticidal activity of plant extracts from the aerial parts of Delphinium leptocarpum Nevski and Delphinium paradoxsun Bge against two major important legume insect pests, cowpea weevils (Callosobruchus maculates) and the rice weevil (Sitophilus oryzae), was studied. According to the screening results, the insecticidal toxicity of the chloroform extract of plant D. leptocarpum N. showed LC50 value of 0,70 mg / mL for adult C. maculates, 0,81 mg / mL for S. oryzae, respectively. The toxicity of the alcoholic extract of D. paradoxsun B. is LC50 0,35 mg / mL for adult C. maculates, 0,39 mg/ mL for S. oryzae, respectively. Exposure to the chloroform extract of D. leptocarpum N. at concentration of 5-10 mg / mL for 24 hours resulted in 83.0100% mortality. After 48 h exposure, the pest mortality was 100%. Under the influence of an alcoholic extract of D. paradoxsun B. at dose of 5-10 mg /mL, the mortality of pests reached 99-100%. The probable use of extracts of D. leptocarpum N. and D. paradoxsun B.as bioinsecticides is discussed here.
In this article, the antioxidant activity of some alkaloids lipid peroxidation (LPO) in rat liver mitochondria has been studied. It has been established that diterpenoid alkaloids: 1-О-benzoylnapelline, napelline and songorine have a protective effect on mitochondria, reducing the damaging effect of Fe2+/ascorbate and the release of malondialdehyde (MDA) into the secondary products of peroxidation. The effect of alkaloids napelline, 1-O-benzoylnapelline and songorine on the processes of MDA formation in rat liver mitochondria in vitro has been studied.Where in at 200 мM concentrations, 1-О-benzoylnapelline inhibited the formation of MDA by 95 %, and the alkaloids napelline and songorine at this concentration inhibited the formation of MDA by 54 and 44 %. From the data obtained, it can be shown that 1-О-benzoylnapelline strongly inhibits the formation of MDA compared to songorine and napelline.
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