Tuğba Güngör scite author profile

Amongst all metabolites of prodrugs after Ssap-NtrB reduction, N-(2,4- dinitrophenyl)-4-nitrobenzamide (3) was efficient and toxic in PC3 cells as comparable as CB1954. Kinetic parameters, molecular docking and HPLC results also confirm that prodrug 3 is better for Ssap-NtrB than 1, 2 and 4 or known cancer prodrugs of CB1954 and SN23862, demonstrating that prodrug 3 is an efficient candidate for NTR based cancer therapy.

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Poly(thieno[3,4-b][1,4]dioxine) and poly([1,4]dioxino[2,3-c]pyrrole) derivatives: p- and n-dopable redox-active electrode materials for solid state supercapacitor applications

Yiğit¹,

Güngör²,

Güllü³

2013

Organic Electronics

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Synthesis and aldose reductase inhibitory activity of N-(quinolinyl thiocarbonyl) glycine derivatives

Nicolaï¹,

Güngör²,

Goyard³

et al. 1992

European Journal of Medicinal Chemistry

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Tuğba Güngör

Biological evaluation and molecular docking studies of nitro benzamide derivatives with respect to in vitro anti-inflammatory activity

PRODRUGS FOR NITROREDUCTASE BASED CANCER THERAPY- 2: Novel amide/Ntr combinations targeting PC3 cancer cells

New nimesulide derivatives with amide/sulfonamide moieties: Selective COX-2 inhibition and antitumor effects

Synthesis and biological evaluation of 2,4,6-trinitroaniline derivatives as potent antitumor agents

Prodrugs for nitroreductase-based cancer therapy-3: Antitumor activity of the novel dinitroaniline prodrugs/Ssap-NtrB enzyme suicide gene system: Synthesis, in vitro and in silico evaluation in prostate cancer

Prodrugs for Nitroreductase Based Cancer Therapy- 1: Metabolite Profile, Cell Cytotoxicity and Molecular Modeling Interactions of Nitro Benzamides with Ssap-NtrB

Poly(thieno[3,4-b][1,4]dioxine) and poly([1,4]dioxino[2,3-c]pyrrole) derivatives: p- and n-dopable redox-active electrode materials for solid state supercapacitor applications

Synthesis and aldose reductase inhibitory activity of N-(quinolinyl thiocarbonyl) glycine derivatives

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