Ultrafine bubbles stabilized by human serum albumin conjugate polyethylene glycol ameliorates the stability of complex as well as the drug payload. Polyethylene glycol presents the crucial role in releasing drug by means of acoustic sound.
The
cause of the Jones–Ray effect has been controversially
debated for years. Ultrafine gas bubbles were employed to lessen the
surface excess of the surface-active impurities adsorbing to the air/water
interface of the salt solutions, which would lead to a direct shift
in surface tension observable by the Wilhelmy plate method. It was
concluded in this study that once the surface excess of the inevitable
impurities in the salts is lessened by the introduction of ultrafine
gas bubbles, which possess great air/water interfacial area, the Jones–Ray
effect becomes nonobservable. Therefore, our finding hypothesized
that the Jones–Ray effect might not originate from salts.
Ultrasound-assisted extraction coupled with gas bubble
flotation
was developed as a green method for extracting β-amyrin fromDischidia major. The solvent system was water:ethanol
(9:1). To improve the adsorption of β-amyrin onto the air/liquid
interface during flotation, surfactants were employed; however, the
positive effect was only observed with cationic surfactants. High-performance
liquid chromatography with spectrophotometric detection (HPLC-PDA)
was, for the first time, applied to quantify the β-amyrin content
in D. major and its extracts. With
the assistance of surfactants, the foam layer collected from flotation
showed high selectivity toward β-amyrin. The product content
was notably increased after surfactants had been removed from the
solution.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.