Structural and mechanical properties of aligned PGS/PCL nanofibers for cornea tissue engineering are studied and compared to natural corneal stroma.

Morphological studies of aligned nanofibers scaffolds made of poly(glycerol sebacate)(PGS)/poly(ϵ‐caprolactone)(PCL) blends for application as corneal tissue scaffolds are presented. Parallel conductive bars are used as ground electrode to generate unidirectional nanofibers. Scaffolds have fibers diameter in the range of 550–300 nm. The structural stability and wettability, especially the in vitro degradation rate, of the electrospun scaffolds can be controlled by regulating the blended ratio of the polymers. The results indicate that PGS/PCL nanofiber scaffolds can be considered as ideal candidates for corneal tissue engineering scaffolds. The particular motivation for this work is to engineer a tissue‐like construct that will mimic the stromal tissue of the cornea.

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