The genus Erythrina is a potential source of chemical constituents, many of which medicinal properties. Although some reviews on chemical constituents of particular Erythrina species could be found, no detailed review covering the chemistry of different Erythrina species has been reported to the best of my knowledge. Therefore, the aim of this review was to compile the phytoconstituents reported from various species of Erythrina. A total of 155 secondary metabolites have been published from 15 species of Erythrina. Among them E. subumbrans and E. variegata consist of the highest number of chemical constituents.
The aim of the study was to evaluate different biological properties of fruits extracts of Ficus erecta (Thunb.). The concentrated methanolic extracts and Kupchan partitions were screened for thrombolytic activity, whereas streptokinase was used as standard antioxidant property by evaluating free radical scavenging effect and determining total phenolic content and cytotoxic activity by brine shrimp lethality bioassay. The highest thrombolytic activity was exhibited by carbon tetrachloride soluble partition (CTP) of the plant (27.53±0.41%) against the standard streptokinase (65.16±0.064%). The IC 50 value of the petroleum ether soluble partition (PEP) was found to be 7.35±0.08 μg/ml, whereas standard ascorbic acid demonstrated IC 50 value of 5.80±0.22 μg/ml. The petroleum ether soluble partition (PEP) also exhibited highest phenolic content (43.69±1.4 mg of GAE/100 g of extractives). A correlation was calculated between total phenolic content and free radical scavenging activity of F. erecta which showed positive result having correlation coefficient (R 2 ) of 0.779. Among the LC 50 values of the plant material, petroleum ether soluble partition (PEP) exhibited the lowest value of 1.20±0.028 µg/ml as compared to the standard vincristine sulphate (0.45±0.003 µg/ml). The present study showed that, the plant F. erecta demonstrated strong cytotoxic and antioxidant property and moderate thrombolytic activity.
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