INTRODUCTION: Across globe research is been conducted to assess the efficacy of many emerging non-thermal technologies in food processes to minimize the deleterious effects of thermal conventional process like, pulsed electric field 1 , Ohmic heating 2 , ultraviolet light 3 , pulsed-light technology 4,5 , ultrasound 6 , cold plasma 7 , high hydrostatic pressure 8 and ultra-high pressure homogenization 9. Consumers crave for food with better nutritional quality, coupled with food safety and use of green technology. 10 The number of potential applications for supercritical fluid extraction (SFE) continues to grow globally, which is verified through the increase in patents deposited in the last few years. It is observed that its application is already part of the present scenery, being mainly impelled by the growing demand of high quality products demand and economy's globalization. Besides that, it also stands out in its use in the commerce of pharmaceutical, food, chemical, and cosmetic materials. The increase in the application of this technology in the industrial area is mainly due to the selectivity, facility, and separation capacity that the technique allows in obtaining a great number of organic compounds, of which many are impossible or nonviable to extract through traditional processes, or those whose purification needs high resolution columns , not always available in the national market, thereby making the utilization very costly. The high utilization of organic solvents in the different industrial processes, such as fat and oil extraction, obtaining bioactive functional compounds, removal of heavy metals, polymer processing, fuel production, among others, represent a globally discussed issue, due to the harm caused to the environment. In light of this picture, in 1987, the Montreal Protocol was introduced, and in 1997 the Kyoto Protocol, which had as the main objective to restrict or eliminate the production and utilization of solvents that cause harm to the ozone layer. 11 The great interest of the scientific community and the industrial sector for SFE is directly related to the restrictions to the use of organic solvents, both in the preparative processes of samples used in the various industries, and in a higher ecological consciousness in the use of different analysis methods involving extraction. The extraction technique most widely known as supercritical fluid Extraction (SFE) Since its inception has been touted for its exceptional performance. 12 Presently, the utilization of SFE is extensively applied not only to the food and drug areas, but also in the areas of toxicology, chemistry, environment, textile, petrochemical, polymers, among others. 13 Significant
