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Injection of LPS into the TMJ significantly altered the masticatory cycle compared with baseline values representing avoidance behaviour due to inflammation of the joint, despite which the horses continued to eat using the contralateral mandible. Lipopolysaccharide administration also led to quidding and a loss of feed efficiency (in some individuals).

Weight bearing (WB) activity is important for healthy skeletal development. The magnitude of loading during WB activities, especially upper limb impacts, has yet to be quantified in children. This study quantifies ground reaction forces (GRF) experienced by children performing WB activities and examines the contribution of body weight (BW) to GRF. Fifty children, aged 8-12 were recruited (34 males). GRF were measured using force plates during 20 upper and lower limb activities (such as landing on the feet and hands). Sex differences in GRF and associations between peak force and BW were examined using independent sample t-tests and linear regressions (p < 0.05), respectively. Lower limb GRF varied from 2-6x BW with no significant sex differences. GRF during upper limb activities varied from 1/3-1.7x BW with males experiencing significantly greater GRF for 25% of activities. BW was significantly associated with peak force in almost all activities; however, GRF variation explained by BW was wide-ranging across activities and not dependent on limb or activity type (static vs dynamic). Therefore, factors other than BW, such as technique, may be important in determining forces experienced by children performing WB activity and should be considered when choosing activities for WB activity interventions.