The endocrine factor plays an important role in the mechanism underlying the increase in working capacity of organism. Other factors also contribute to this increase.Key Words: hypothyroidism; hyperthyroidism; adrenalectomy; hydrocortisone; dexasone Although the effects of low-intensity laser radiation (LILR) on the organism have been extensively investigated, much remains unclear. There is evidence that these effects are mediated by the endocrine system, primarily, via hypothalamic--hypophyseal--thyroid and hypothalamic--hypophyseal-adrenal axises [1,2].Previously, we showed that LILR increases working capacity of animals more than 2-fold with concomitant activation of thyroid gland and adrenals. Since thyroid and glucocorticoid hormones are involved in the maintenance and preservation of stability of organism exposed to various pathogenic factors, we decided to evaluate their role in the mechanism responsible for the LILR-induced increase in the working capacity of rats, using the models of hypoand hyperthyroidism, adrenalectomy, and treatment with dexasone and hydrocortisone.
MATERIALS AND METHODSExperiments were performed on 169 male outbred albino rats (initial body weight 160-180 g).Physical load was modeled with using of an 8-track treadmill with automatically regulated track speed, which allowed us to record the time during which the animals could run and the covered "distance." In this study track speed was 20 m/min.
In the context of strengthening the fight against doping and limiting the use of synthetic pharmaceuticals, the effective remedies to increase physical performance and accelerate the recovery of athletes are being sought. One of such remedies is exposure to low-level laser radiation (LLLR, LLLT). The study was aimed to investigate the physiological response of highly qualified female rowers’ functional systems to the LLLR irradiation course. To monitor the body of athletes, we used laser Doppler flowmetry (LDF), mathematical analysis of heart rate, neuroenergy mapping, as well as pedagogical testing using the Concept 2 simulator. After irradiation of the neck in the projection of the carotid arteries with pulsed infrared LLLR, the blood perfusion rate increased by 38% (р < 0.05) and cell oxygen utilization rate increased by 48% (р < 0.05). The decrease in the hemoglobin oxygen saturation by 16% (р < 0.05) was also observed. Due to LLLT, the activity of the autonomous regulation mechanism increased with an increase in the total power of the heart rate variability spectrum (TP) by 41% (р < 0.05), and in high-frequency power (HF) by 73% (р < 0.05). The influence of central mechanism decreased with a decrease in amplitude mode (AMo) by 71% (р < 0.05), and in stress-index (SI) by 175% (р < 0.05). Irradiation by LLLR promoted the efficiency of oxygen delivery to certain cerebral cortex areas with the increase of SPL. Аfter LLLT, the speed of 2000 meters distance "passing" by athletes also increased by 3.32% (p > 0.05). The discovered effects of LLLT allow one to expand the range of physiotherapeutic agents that enhance the special physical performance of athletes and accelerate recovery.
Monitoring of biochemical parameters of blood allows to determine the individual characteristics of athletes’ body and evaluate the effectiveness of building a training process. The increasing volume of physical activity during the preparatory period forces us to search for means of rapid increase in the functional level state and physiological reserves of an organism. In this regard, as one of the methods, the physiotherapeutic course effect of low-intensity laser radiation can be used. It was revealed that a specific physical load leads to a significant increase in lactate and total blood protein levels. So, in short-trackers in a state of relative physiological rest, the concentration of lactate was 2,77±0,24 mmol/l, which is much higher than the norm (the norm is 1,3±0,35 mmol/l). After the course of low-intensity laser radiation, the lactate level decreased insignificantly (2,52±0,19 mmol/l), but did not reach normal values. After the action on the body of a specific physical load, lactate concentration increased significantly, reaching a level equal to 9,24±0,43 mmol/l. The conducted course laser therapy allowed to reliably (р 0,05) lower its level to 6,25±0,32 mmol/l. In this case, urea and creatinine had only a tendency to increase. Thus, low-intensity laser radiation against the background of a specific physical load makes it possible to bring the investigated parameters close to the boundary of the physiological norm.
Aim. The article deals with the effect of a whey-based product on the metabolic processes, character, and local mechanisms of the microcirculation in athletes involved in track-and-field athletics. Materials and methods. 32 male athletes participated in the study. The microcirculation was studied with the help of the LAKK-M laser analyzer. The calculations were conducted by using a special software package (version 2.0.0.423, LAZMA, Russia). Results. It is established that a course of the MDX Multicomplex bioproduct increases blood perfusion in the microcirculatory bloodstream by 34% and erythrocyte fluctuation by 66%, which improve the efficiency of metabolic processes. Bloodstream modulation is provided by the enhanced performance of the local active regulatory mechanisms. A statistically significant increase of 42% is registered in the endothelium-dependent mechanism, the increase of 32% and 23% is found in the myogenic and neurogenic mechanisms respectively. The contribution of the passive regulatory mechanisms reduces as a result of chest and heart muscle performance. The physiologically active substances of the bioproduct are involved in the vasodilation of microvessels and redox reactions at the cellular level. A 22% increase in NADH reduced coenzyme and a 9% decrease in FAD oxidized coenzyme indicate a decrease in mitochondrial activity in the absence of physical exertion and, indirectly, confirm the complete restoration of the energy reserves. Conclusion. The data obtained proves the optimization of metabolic processes in the microcirculation as an effect of the MDX Multicomplex bioproduct.
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