The endocrine factor plays an important role in the mechanism underlying the increase in working capacity of organism. Other factors also contribute to this increase.Key Words: hypothyroidism; hyperthyroidism; adrenalectomy; hydrocortisone; dexasone Although the effects of low-intensity laser radiation (LILR) on the organism have been extensively investigated, much remains unclear. There is evidence that these effects are mediated by the endocrine system, primarily, via hypothalamic--hypophyseal--thyroid and hypothalamic--hypophyseal-adrenal axises [1,2].Previously, we showed that LILR increases working capacity of animals more than 2-fold with concomitant activation of thyroid gland and adrenals. Since thyroid and glucocorticoid hormones are involved in the maintenance and preservation of stability of organism exposed to various pathogenic factors, we decided to evaluate their role in the mechanism responsible for the LILR-induced increase in the working capacity of rats, using the models of hypoand hyperthyroidism, adrenalectomy, and treatment with dexasone and hydrocortisone.
MATERIALS AND METHODSExperiments were performed on 169 male outbred albino rats (initial body weight 160-180 g).Physical load was modeled with using of an 8-track treadmill with automatically regulated track speed, which allowed us to record the time during which the animals could run and the covered "distance." In this study track speed was 20 m/min.
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