Plants are excellent sources of secondary metabolites that have been used for the treatment of human diseases. The plant Momordica cymbalaria contains different types of phytochemicals like phenols, steroids, flavonoids, alkaloids and tannins. The present investigation was carried out to determine the bioactive compounds present in the different plant parts of Momordica cymbalaria by Gas chromatography-Mass spectroscopy (GC-MS) technique. Chromatograms and bioactive compounds of in vivo leaf, root and in vitro leaf callus methanolic extracts of Momordica cymbalaria are derived by GC-MS technique. 37 compounds were found in leaf methanolic extracts, 20 compounds in vitro leaf callus methanolic extracts and 18 compounds in root methanolic extracts. These are important bioactive compounds n-Hexadecanoic acid, 9-octadecenoic acid methyl ester,
Muntingia calabura, a well-known medicinal plant has been documented to possess various bioactive molecules from the Muntingaceae family. In the present study, we investigated the phytochemical screening by qualitative and quantitative analysis from leaf and root parts of M. calabura. The preliminary screening was done by cold maceration technique with methanol, butanol, chloroform, ethanol and hexane solvents. The qualitative phytochemical screening of these plant parts revealed the presence of alkaloids, phenols, flavonoids, tannins and saponins. The results revealed that the methanol solvents from both the explants had given good results compared to the other solvents. As per results of quantitative analysis, the determined highest alkaloid content was 51.37 ± 0.78 BEA/gm in leaf and 49.37 ± 0.77 BEA/gm in root followed by tannins, phenols, saponins and flavonoids. The total anti-oxidants were determined as 27.086 ± 0.52 AAE/gm in leaf and 26.816 ± 0.69 in the root. Based on the results, the present study suggests that the revealed phytochemicals possess potential anti-oxidants and lead to the isolation of new bioactive compounds in M. calabura.
The study aimed to identify bioactive compounds in <i>Muntingia calabura</i> leaf and root methanolic extracts. The Gas Chromatography and Mass Spectroscopy (GC-MS) technique were used to identify bioactive compounds. GC-MS analysis revealed 38 compounds in the leaf and 15 compounds in the root methanolic extracts of <i>M. calabura</i>. The prime potent compound found in leaf extract is 2-{3-[(E)-2-(1H-indol-3-yl)ethenyl]-1,2,4-oxadiazol-5-yl}phenol with 5.78% peak area and cholest-4-en-6-on-3-ol is found in root extracts, has the highest 63.7% peak area and another potent compound Lupeol has 7.3% peak area. The bioactive compounds identified in <i>M. calabura</i> have antibacterial activity against various bacterial strains such as gram-positive and gram-negative bacteria, which showed the efficacy of <i>in vivo</i> plant extracts. These findings validate the therapeutic potentiality of <i>M. calabura</i> leaf and root samples. Furthermore, these screened potential bioactive compounds can be used effectively for biomedical and therapeutic applications.
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