Background
Olive leaf extract (OLE), a naturally extracted product from olive leaves, contains oleuropein and other bioactive phenolic compounds. Oleuropein was identified to have various medical properties. It was also found to inhibit the effects of both acute and chronic UVB‐induced skin damage as well as accelerate wound healing activity.
Aims
To evaluate the efficacy of olive leaf extract–containing cream on facial rejuvenation.
Methods
This is a prospective pilot study with a total of 36 participants, who presented with photoaging skin. All participants applied the olive leaf extract–containing cream (SUPERHEAL™ O‐Live Cream, PhytoCeuticals, Inc, USA) to their whole face twice daily for 2 months. Primary outcomes measured in the study were the changes in the biophysical properties of the skin assessed with the following parameters: melanin and erythema index, transepidermal water loss (TEWL), skin hydration, skin pH, sebum level, texture, and wrinkles.
Results
After 2 months, TEWL decreased significantly (P = .007) and maintained the results 1 month after discontinuation of the treatment (P = .007). Skin hydration also increased significantly after 2 months (P = .004). Wrinkles improved significantly on all follow‐ups (P < .001, P = .001, P = .001, respectively). An image of the skin captured using Visioscan® showed improvement of the skin texture 2 months after treatment. Majority of the participants (64%) noted improvement in their skin texture.
Conclusion
Olive leaf extract–containing cream provided benefits on skin rejuvenation in human skin.
BackgroundDermatitis can impair the quality of life (QoL) of patients. Knowledge of the QoL‐associated factors and the impact of patch testing on QoL is limited.ObjectivesTo identify demographic and clinical factors affecting QoL, and to measure the impact of patch testing on QoL of dermatitis patients.MethodsThe data and Dermatology Life Quality Index (DLQI) questionnaires of 519 dermatitis patients were analyzed. Of these, 107 underwent patch testing and completed the questionnaires two times (once before testing and again 60 days afterward).ResultsThe overall mean (±standard deviation) DLQI was 9.5 (±6.4). Patients aged 20 to 59 years and those who had more frequent disease exacerbations demonstrated significantly higher DLQIs. For each DLQI question, being female and aged 20 to 59 years were associated with impairments of various aspects of life, whereas the anatomical site of dermatitis impacted each question differently. The DLQI scores of the patients undergoing patch testing decreased significantly, irrespective of whether the test results were positive or negative.ConclusionsBeing of a working age and having more frequent disease exacerbations had negative QoL impacts. In addition, patch testing improved almost every aspect of the DLQI.
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