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This study aims to determine the relationship between spermidine (SPD) and spermine (SPM) with the incidence of atherosclerosis in population of Iraqi patients in comparison with controls. A total of 128 atherosclerosis patients (64 male and 64 female) were included in the present study (aged 45-70 years). They were categorized into two groups: a group that underwent percutaneous coronary intervention catheterization (PCI) and a group that underwent diagnostic catheterization (DIG). 64 age matched, apparently healthy individuals (showing no symptoms of heart disease) of both men and women were also included in the control group (C). Sera were used as samples of the present study; the main measurements included SPD and SPM levels using the HPLC method. Results showed that serum levels of SPD were 631.53 ± 35.637, and 540.49 ± 44.564µg/ml in PCI and DIG patients, respectively. These levels showed significant increases (p˂0.001) when compared to their levels (29.162 ± 6.151µg/ml) in sera of healthy controls. On the other hand, the SPM levels were (159.98 ± 15.981, and 169.85 ±14.606 µg/ml) in PCI and DIG patients, respectively, which also show significant increases (p˂0.001) when compared with the SPM levels (24.26 ± 4.613 µg/ml) in the control group. Moreover, the changes in SPD and SPM levels differed significantly (p˂0.001, and p˂0.05, respectively) according to gender in patient groups. Moreover, it was found that there were positive correlations between sera levels of SPD and SPM in atherosclerosis patients with the levels of white blood cells (WBC) (r=0.58, p˂0.05, r=0.55, p˂0.05), neutrophils (r=0.54, p˂0.05, r=0.51, p˂0.05), lymphocytes (r=0.46, p˂0.05, r=0.48, p˂0.05) and red blood cells (RBC) (r=0.43, p˂0.05, r=0.60, p˂0.01). These results demonstrated that SPD and SPM levels were altered in sera of atherosclerosis patients when compared with the control group. In addition, the data indicated that these patients’ gender played a role in their levels. Generally, correlations were observed among the SPD and SPM levels, the white blood cell differential, and the red blood cells in the sera of atherosclerosis patients.

Infertility is the inability to conceive a child for more than one year. The present study indicates that the obesity associated with infertility. The aim of the study to determine follicle stimulating hormone, luteinizing hormone, testosterone hormone and prolactin levels. and cholesterol and triglyceride concentration in 2 nd inferetid women. This study was carried out at kamal al-samaarai hospital the data were collected from 95 secondary infertilial women were age between 16-45 years old and grouped them in to obese (n = 46) and non obese(n = 49). There was no significant difference between the two groups (p <0.05). Body mass index in Infertile obese women is slightly higher than non obese Infertile women which is statistically significant (P<0.001). However LH, TSH, cholesterol and triglyceride concentration in obese infertile women is significantly higher than non obese infertile women (p >0.05).The BMI was correlated positively with triglyceride in obese group while BMI was positive correlation highly significant with cholesterol in non obese group. Regression analysis revealed obese to be strongly associated with observed infertility. The elevated prolactin values in secondary infertile women clearly shows that there is a mechanism operating at the anterior pituitary level which shows an abnormal distribution of FSH and LH which may further explain the abnormal delay ovum maturation. This study also indicates obese associated with infertile more than non obese women.

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The erythrocyte sedimentation rate (ESR) is commonly used to assess the acute phase of the inflammatory response and to diagnose conditions associated with acute and chronic inflammation, including infections, cancers, and autoimmune diseases. Packed Cell Volume (PCV) is the height of the red cell column to the total height of the column of whole blood. This study included 100 healthy subject divided into two groups: females group (50) and males group (50). The increase in Erythrocyte Sedimentation Rate (E.S.R) was higher in women group than in men group. The result showed a negative correlation between the Packed Cell Volume (PCV) and ESR while there was a positive correlation between ESR with age and glucose.