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This paper describes an on-die lightweight nanoAES hardware accelerator, fabricated in 22 nm tri-gate high-k/metal-gate CMOS, targeted for ultra-low power symmetric-key encryption and decryption on mobile SOCs. Compared to conventional 128 bit AES implementations, this design uses a single 8 bit Sbox circuit along with ShiftRows byte-order data processing to compute all AES rounds in native composite-field. This approach along with a serial-accumulating MixColumns circuit, area-optimized encrypt and decrypt Galois-field polynomials and integrated on-the-fly key generation circuit results in a compact encrypt/decrypt layout occupying 2200/2736 m and lowest-reported gate count of 1947/2090 respectively, while achieving: (i) maximum operating frequency of 1.133 GHz and total power consumption of 13 mW with leakage component of 500 W, measured at 0.9 V, 25 C, (ii) nominal AES-128 encrypt/decrypt throughput of 432/671 Mbps respectively, with peak energy-efficiency of 289 Gbps/W measured at near-threshold operation of 430 mV (11 higher than previously reported implementations), (iii) encrypt/decrypt latencies of 336/216 cycles and total energy consumption of 3.9/2.5 nJ respectively, (iv) wide operating supply voltage range with robust sub-threshold voltage performance of 45 Mbps, 170 W, measured at 340 mV, 25 C and (v) first-reported Galois-field polynomial-based micro-architectural co-optimization, resulting in distinct area-optimized encrypt and decrypt polynomials with up to 9% area reduction at iso-performance.Index Terms-Advanced encryption standard, composite-field polynomial arithmetic, encryption hardware accelerator, lightweight crypto, on-the-fly key-generation, security, ultra-low power AES.

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Although the clinical picture of cerebral malaria in children has been reported extensively, scant information is available about cerebral malaria in adults. This report relates to one of the largest series of adult cases of cerebral malaria patients ever described. At Rourkela, in eastern India, 526 adults (aged >12 years) who each satisfied the World Health Organization's criteria for cerebral malaria were admitted to Ispat General Hospital between 1995 and 2001. These cases represented 18% of the 2994 adult patients who were admitted with Plasmodium falciparum malaria over the same period. Most (76%) of the adult cases of cerebral malaria were male, 48% were aged 21-40 years, and only 4% were older than 60 years. The most common presenting symptoms were fever (97.7%), vomiting (54.6%), headache (30.8%) and seizures (17.1%). Most (62.4%) of the cases had associated severe complications: jaundice (47.5%), acute renal failure (28.9%), and/or severe anaemia (9.7%). Overall, 175 (23%) of the cases were fatal, mortality being particularly high (59%) among those with multi-organ failure. Of the fatal cases, 107 (61%) died within the first 24 h of hospitalization, presumably indicative of late presentation. As the management of multiple complications may be inadequate at primary centres, early referral to higher centres is recommended.

pesticides residue poses serious concerns to human health. the present study was carried out to determine the pesticide residues of peri-urban bovine milk (n = 1183) from five different sites (Bangalore, Bhubaneswar, Guwahati, Ludhiana and Udaipur) in India and dietary exposure risk assessment to adults and children. pesticide residues were estimated using gas chromatography with flame thermionic and electron capture detectors followed by confirmation on gas chromatographymass spectrometer. The results noticed the contamination of milk with hexachlorocyclohexane (HCH), dichloro-diphenyl trichloroethane (DDT), endosulfan, cypermethrin, cyhalothrin, permethrin, chlorpyrifos, ethion and profenophos pesticides. the residue levels in some of the milk samples were observed to be higher than the respective maximum residue limits (MRLs) for pesticide. Milk samples contamination was found highest in Bhubaneswar (11.2%) followed by Bangalore (9.3%), Ludhiana (6.9%), Udaipur (6.4%) and Guwahati (6.3%). The dietary risk assessment of pesticides under two scenarios i.e. lower-bound scenario (LB) and upper-bound (UB) revealed that daily intake of pesticides was substantially below the prescribed acceptable daily intake except for fipronil in children at UB. The non-cancer risk by estimation of hazard index (HI) was found to be below the target value of one in adults at all five sites in India. However, for children at the UB level, the HI for lindane, DDT and ethion exceeded the value of one in Ludhiana and Udaipur. Cancer risk for adults was found to be in the recommended range of United States environment protection agency (USEPA), while it exceeded the USepA values for children.

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