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Rosai-Dorfman disease (RDD), also known as sinus histiocytosis with massive lymphadenopathy is a rare disease involving the lymph nodes. Extranodal RDD involving the thyroid is extremely rare. So far, six cases of RDD involving thyroid have been reported in the literature; all have occurred in females with a mean age of 56.3 years. Clinically, radiologically and cytologically, all the cases were initially diagnosed as thyroid malignancies with lymph nodal metastasis. The final diagnosis was made histologically only after total thyroidectomy. We herein, present a seventh case of RDD involving the thyroid in a 15-year-old female, diagnosed first on fine needle aspiration cytology (FNAC). We conclude that FNAC is a useful diagnostic procedure for RDD involving thyroid; it can avoid an unnecessary thyroidectomy.

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Histological examination showed stratified squamous epithelial lining with thin rete ridges. The subepithelial ABSTRACT Reactive hyperplastic outgrowths are seen in the oral cavity due to chronic irritation by plaque, calculus, overhanging margins, trauma and dental appliances. Irritation fibroma represents a reactive focal fibrous hyperplasia due to trauma or local irritation. We report a case of irritation fibroma of right lateral border of tongue in a 46-year-old female.

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Abstract:Granuloma pyogenicum or Pyogenic granuloma is an inflammatory hyperplasia affecting the oral tissues. It is a tumour-like growth of the oral cavity, which usually arises in response to nonspecific infection, irritation, physical trauma or hormonal factors. The condition is frequently associated with periodontal pain and discomfort, in some cases interfering with mastication and creating esthetic problems. The condition is frequently associated with recurrence, and has more predilections towards females. We report a case of pyogenic granulomaof gingiva in 12 years old male.