The recent development of the analytical techniques offers the unprecedented possibility to study simultaneously concentration of dozens of elements in the same biological matrix sample of 0.5–1.0 g (multielement profiles). The first part of this essay entitled “Think globally… An outline of trace elements in health and disease” aims to introduce the reader to the fascinating field of elements, there importance to our nutrition, their essentiality, deficiency, toxicity and bioavailability to the body and their overall role in health and disease, including the genetic metabolic impairments. In the second part of the essay entitled “… and act locally. The multielement profile of depression” we aimed to show the potential of such a hair multielement profile analysis for the study of human depression in a randomized, double blind, prospective, observational, cross-sectional, clinical, epidemiological, and analytical study. The preliminary results of this ongoing study lead us to put forward the hypothesis that the metabolic origin of depression may be due to some “energostat” failure, probably located in the thalamus, and activated by several essential element deficiencies.

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Hair appears to be a valuable and robust biological indicator tissue for assessing long-term iodine status. We propose that an adequate iodine status corresponds with hair iodine uptake saturation of 0.565-0.739 μg/g (55-65%).

Introduction: Croatia is introducing the new Law on Protection of Persons with mental disorders on January 1, 2015. Major changes are related to the terms of involuntary admissions, thus aiming to improve protection of persons with mental disorders within psychiatric care. Aim: Aim of this paper is to compare mental health legislation and position of mentally ill people in five EU countries, namely Croatia, Germany, Spain, Sweden and UK. Methods: Methods of descriptive analysis are employed to explore similarities and differences among countries in relation to the four following indicators-involuntary admission procedure, forms of involuntary treatment, maximum duration of involuntary treatment and patients' legal right to complain. Results: Despite all being in the EU, countries included in the study vary substantially in their legislation for the practice of involuntary hospital admission which will be presented in details. Conclusion: How involuntary treatments should be legislated and regulated is highly controversial. We believe that EU countries should join forces to create a common understanding of this issue because legal differences could lead to substantial discrepancies in human right protection practices regarding persons with mental disorders.

Sindrom sagorijevanja na poslu (engl. burnout syndrome) rezultat je kroničnog stresa na poslu, uz korištenje relativno neučin-kovitih strategija suočavanja sa stresom, a mnogobrojne studije provedene na medicinskim sestrama i liječnicima potvrđuju kako su mu posebno izloženi zdravstveni radnici. Tijekom pandemije bolesti COVID-19, zdravstveno osoblje postalo je izloženo i dodatnim stresnim čimbenicima, što povećava mogućnost razvijanja sindroma sagorijevanja. Ovaj pregledni rad donosi najnovije podatke o stopi prevalencije sindroma sagorijevanja u zdravstvenih radnika (medicinskih sestara i liječnika), prije i za vrijeme krize izazvane virusom SARS-CoV-19, te razmatra čimbenike koje utječu na razvitak sindroma sagorijevanja, s ciljem identificiranja čimbenika koji djeluju protektivno na mentalno zdravlje zdravstvenih djelatnika. Prikupljeni podaci u brojnim studijama potvrđuju kako je od velikog značenja pravovremeno razviti strategije prevencije, liječenja i rehabilitacije osoba sa sindromom sagorijevanja, čime bi se održalo mentalno zdravlje medicinskog osoblja, ali i kvaliteta skrbi koja se pruža pacijentima unutar zdravstvenog sustava.

Concentrations of different BE are associated with different schizophrenia symptoms. Maximal correlation between BPRS and BE may be achieved with the weighted linear composite of negative schizophrenia symptoms and copper (Cu), lead (Pb), lithium (Li) and cobalt (Co).

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