“…We have been under constant pressure to reduce the daily salt intake for decades, and thus reduce available dietary iodine intake. Our method of analyzing trace element median derivatives [7,19] . Hair is itself a dynamic tissue structure -some 90% of hair follicles are active (anagen phase), some 10% are dormant (telogen phase), and some degenerate only to rise anew some other time [20].…”
Section: Resultsmentioning
confidence: 99%
“…The aim of this paper is to explore how much iodine may be found in the human hair of an apparently healthy population, to study the frequency distribution of the observed iodine concentrations relative to the sex, and to estimate the possible risk of iodine deficiency and overexposure [7]. We have previously demonstrated the high reliability of hair for the multielement profile analysis [8]; the hair is easily accessible growing biological structure of keratin fiber protein [9], easy to store and transport, and it usually has concentrations of iodine well above the detection limits necessary for accurate chemical analysis.…”
Section: Discussionmentioning
confidence: 99%
“…Our detection limit for hair iodine was 0.01 µg·g -1 , and the 6 coefficient of variation between the assays was 0.408 (SD/Mean) [8]. To scrutinize the hair iodine concentration frequency distribution we used the median derivative model to fit the sigmoid logistic regression analysis function for men and women separately (Appendix) [7,19]:…”
“…We have been under constant pressure to reduce the daily salt intake for decades, and thus reduce available dietary iodine intake. Our method of analyzing trace element median derivatives [7,19] . Hair is itself a dynamic tissue structure -some 90% of hair follicles are active (anagen phase), some 10% are dormant (telogen phase), and some degenerate only to rise anew some other time [20].…”
Section: Resultsmentioning
confidence: 99%
“…The aim of this paper is to explore how much iodine may be found in the human hair of an apparently healthy population, to study the frequency distribution of the observed iodine concentrations relative to the sex, and to estimate the possible risk of iodine deficiency and overexposure [7]. We have previously demonstrated the high reliability of hair for the multielement profile analysis [8]; the hair is easily accessible growing biological structure of keratin fiber protein [9], easy to store and transport, and it usually has concentrations of iodine well above the detection limits necessary for accurate chemical analysis.…”
Section: Discussionmentioning
confidence: 99%
“…Our detection limit for hair iodine was 0.01 µg·g -1 , and the 6 coefficient of variation between the assays was 0.408 (SD/Mean) [8]. To scrutinize the hair iodine concentration frequency distribution we used the median derivative model to fit the sigmoid logistic regression analysis function for men and women separately (Appendix) [7,19]:…”
“…The aim of this study was to explore how much iodine may be found in the hair of an apparently healthy population having an adequate iodine dietary intake, to study the frequency distribution of the observed iodine concentrations relative to sex, and to estimate the levels that may be associated with a possible risk of iodine deficiency and overexposure (16). We have previously demonstrated the high reliability of hair for multielement profile analysis (17); hair is easily accessible, easy to store and transport, and it usually has concentrations of iodine well above the detection limits necessary for accurate chemical analysis.…”
Hair appears to be a valuable and robust biological indicator tissue for assessing long-term iodine status. We propose that an adequate iodine status corresponds with hair iodine uptake saturation of 0.565-0.739 μg/g (55-65%).
“…The Qtiplot Data Analysis and Scientific Visualisation program was used for this analysis (www.soft.proindependent.com/qtiplot.html). We used this model for assessing the respective environmental silver body exposure and iodine nutritional status (19,20).…”
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