Aim To assess the epidemiological and clinical factors that influence the prognosis of oral and oropharyngeal squamous cell carcinoma (SCC). Methods One hundred and twenty-one cases of oral and oropharyngeal SCC were selected. The survival curves for each variable were estimated using the Kaplan-Meier method. The Cox regression model was applied to assess the effect of the variables on survival. Results Cancers at an advanced stage were observed in 103 patients (85.1%). Cancers on the tongue were more frequent (23.1%). The survival analysis was 59.9% in one year, 40.7% in two years, and 27.8% in 5 years. There was a significant low survival rate linked to alcohol intake (p = 0.038), advanced cancer staging (p = 0.003), and procedures without surgery (p < 0.001). When these variables were included in the Cox regression model only surgery procedures (p = 0.005) demonstrated a significant effect on survival. Conclusion The findings suggest that patients who underwent surgery had a greater survival rate compared with those that did not. The low survival rates and the high percentage of patients diagnosed at advanced stages demonstrate that oral and oropharyngeal cancer patients should receive more attention.
Objective
To analyze published scientific evidence about the most common orofacial disorders in children with microcephaly associated with ZIKV infection.
Methods
Through a scoping review, we respond to the search question was formulated: "What are the orofacial alterations in children with microcephaly associated with ZIKV?" It was performed a search in PubMed, EMBASE, Scopus, and Health Virtual Library. It was selected papers wrote in English, Portuguese, or Spanish. An evidence quality analysis was performed using the Agency for Healthcare Research and Quality classification.
Results
It was included 11 studies performed in the Brazilian Northeast region. The studies were carried out between 2018 and 2020. The main related alterations were delay in the tooth‐eruption and deformation in the oral structures.
Conclusion
The results observed in our work show moderate scientific evidence regarding the association of ZIKV with orofacial alterations in children with microcephaly due to the classifications of the quality of evidence of each one of the included studies. The main changes reported were in the chronology of tooth eruption, alteration in teeth, and oral structures.
This paper presents an unusual case of gingival ALCL, which mimicked a benign hyperplastic lesion that occurred in a 57-year-old white man representing the first clinical manifestation of acquired immunodeficiency syndrome (AIDS). The patient was referred to the Dental Clinic of PUCPR complaining of a lobulated nodule on the gingiva of his upper central incisors. The presence of advanced chronic periodontitis and dental plaque raised suspicion for a benignancy. An excisional biopsy was performed, and large pleomorphic cells with an abundant cytoplasm, sometimes containing prominent nucleoli and “Hallmark” cells, were observed through hematoxylin and eosin staining. The tumor cells showed strong CD30 expression, EMA, Ki-67, and LCA, and negative stain for p80NPM/ALK, CKAE1/AE3, CD20, CD3, CD56, and CD15. The final diagnosis was ALCL (ALK-negative). Further laboratory tests revealed positivity for human immunodeficiency virus (HIV). The patient was submitted to chemotherapy, but four months after diagnosis, the patient died due to pneumonia and respiratory failure. Oral anaplastic large-cell lymphoma (ALCL) is a rare disorder. Only 5 cases involving the gingiva have been reported, and to our knowledge, this is the first case reported of the ALCL, which mimicked a hyperplastic benignancy as the first clinical manifestation of AIDS.
Objetivo: Avaliar o conhecimento e o uso dos procedimentos que envolvem a biossegurança por cirurgiões dentistas e assistentes de saúde bucal em um município do sertão de pernambucano, buscando averiguar a compreensão da necessidade e da importância da utilização da biossegurança.
Métodos: Estudo observacional descritivo realizado através de questionário aplicado para os profissionais da área odontológica vinculados ao Sistema Único de Saúde (SUS) do município de Arcoverde, Pernambuco, Brasil. A amostra foi constituída de 29 profissionais da área odontológica que responderam ao questionário, sendo 9 dentistas e 20 auxiliares.
Resultados: Cem por cento dos profissionais afirmam lavar as mãos antes e depois dos procedimentos. Apenas 20% dos ASB lavam o instrumental em pia fora do consultório; 90% costumam fazer a assepsia da cadeira odontológica após cada atendimento; 95% costumam fazer a assepsia da cuspideira e do equipo/cárter após cada atendimento.
Conclusão: Os profissionais possuem conhecimento satisfatório acerca da biossegurança no consultório odontológico. Contudo, deve-se uma atenção especial ao uso de luvas estéreis e de campo cirúrgico durante os procedimentos necessários, bem como à disponibilização de equipamentos de proteção individual aos pacientes, a fim de minimizar o risco de contaminação cruzada.
Descritores: Contenção de riscos biológicos. Saúde bucal. Sistema Único de Saúde. Educação continuada.
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