Introduction: Exercise reduces arterial and central venous blood pressures during recovery, which contributes to its valuable anti-hypertensive effects and to facilitating hypervolemia. Repeated sprint exercise potently improves metabolic function, but its cardiovascular effects (esp. hematological) are less well-characterized, as are effects of exercising upper versus lower limbs. The purposes of this study were to identify the acute (<24 h) profiles of arterial blood pressure and blood volume for (i) sprint intervals versus endurance exercise, and (ii) sprint intervals using arms versus legs.Methods: Twelve untrained males completed three cycling exercise trials; 50-min endurance (legs), and 5*30-s intervals using legs or arms, in randomized and counterbalanced sequence, at a standardized time of day with at least 8 days between trials. Arterial pressure, hemoglobin concentration and hematocrit were measured before, during and across 22 h after exercise, the first 3 h of which were seated rest.Results: The post-exercise hypotensive response was larger after leg intervals than endurance (AUC: 7540 ± 3853 vs. 3897 ± 2757 mm Hg·min, p = 0.049, 95% CI: 20 to 6764), whereas exercising different limbs elicited similar hypotension (arms: 6420 ± 3947 mm Hg·min, p = 0.48, CI: −1261 to 3896). In contrast, arterial pressure at 22 h was reduced after endurance but not after leg intervals (−8 ± 8 vs. 0 ± 7 mm Hg, p = 0.04, CI: 7 ± 7) or reliably after arm intervals (−4 ± 8 mm Hg, p = 0.18 vs. leg intervals). Regardless, plasma volume expansion at 22 h was similar between leg intervals and endurance (both +5 ± 5%; CI: −5 to 5%) and between leg and arm intervals (arms: +5 ± 7%, CI: −8 to 5%).Conclusions: These results emphasize the relative importance of central and/or systemic factors in post-exercise hypotension, and indicate that markedly diverse exercise profiles can induce substantive hypotension and subsequent hypervolemia. At least for endurance exercise, this hypervolemia may not depend on the volume of post-exercise hypotension. Finally, endurance exercise led to reduced blood pressure the following day, but sprint interval exercise did not.

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Just a decade ago Vision and Change in Undergraduate Biology Education: A Call to Action was released, catalyzing several initiatives to transform undergraduate life sciences education. Among these was the Partnership for Undergraduate Life Sciences Education (PULSE), a national organization commissioned to increase the adoption of Vision and Change recommendations within academic life sciences departments. PULSE activities have been designed based on the recognition that life sciences departments and faculty are embedded within institutions of higher education which, similar to other large organizations, are complex systems composed of multiple, interconnected subsystems. The organizational change research suggests that effecting large-scale changes (e.g., undergraduate STEM education transformation) may be facilitated by applying systems thinking to change efforts. In this paper we introduce the approach of systems thinking as a professional development tool to empower individual STEM faculty to effect department-level transformation. We briefly describe a professional development experience designed to increase life sciences faculty members’ understanding of systems thinking, present evidence that faculty applied a systems thinking approach to initiate department-level change, and discuss the degree to which transformation efforts were perceived to be successful. Though focused on faculty in the life sciences, our findings are broadly transferable to other efforts seeking to effect change in undergraduate STEM education.

This study examined the effects of an external nasal dilator (END) on sedentary and aerobically trained women using the blood lactate threshold as a measure of aerobic performance. Three groups of women (sedentary, pre-season, in-season) participated in the study: nine sedentary college students (age 19 +/- 1.0 y), eight pre-season college athletes (age 20 +/- 2.3 y), and six in-season college rowers (age 20 +/- 1.7 y). A two-way repeated-measures design was used with subjects in each group being exposed to both conditions (with END and without END). The first two groups performed two incremental exercise tests in random order on a cycle ergometer, and the third group performed the tests on a rowing ergometer. Participants in each group wore an END strip for only one of the tests. Venous blood was collected at rest, during the final 30 seconds of each stage, and 1 and 3 minutes into the recovery period for the determination of blood lactate concentration and identification of the blood lactate threshold. No significant differences (P = 0.05) were found in blood lactate concentration at the lactate threshold between conditions for either group (sedentary: with END 2.51 +/- 1.18 mmol x L(-1), without END 2.56 +/- 0.84 mmol x L(-1); pre-season: with END 2.93 +/- 0.97 mmol x L(-1), without END 2.81 +/- 1.15 mmol x L(-1); and in-season: with END 3.93 +/- 0.50 mmol x L(-1), without END 3.49 +/- 0.387 mmol x L(-1)). We conclude that (a) the END did not improve the lactate threshold in either sedentary or trained college-age women, and (b) the END did not result in lower blood lactate levels during moderate to high-intensity exercise in the three groups examined in this study.

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