SYNOPSIS
Skin temperature biofeedback was used in treating two groups of patients with migraine. The experimental group received true auditory feedback controlled by increases in skin temperature of their fingers, while the control group received a similar “positive” signal independent of skin temperature changes and controlled by the investigator. The true feedback group increased their skin temperature significantly more (p < 0.05) than the control group, but both groups showed similar improvement in headaches. This study suggests that biofeedback techniques are useful in treating patients with migraine, and the mechanism, presumably a placebo effect, is independent of peripheral skin temperature changes.
A B S T R A C T A technique was developed and evaluated using the exponential infusion of positron-emitting diffusible tracers Actual and estimated flow correlated significantly for both the 14 KH-RBC hearts infused with H2'50 (r = 0.90, n = 89 determinations) and the 3 KH-RBC hearts infused with ["Cibutanol (r = 0.93, n = 13 determinations). In addition, the required exponentially increasing arterial tracer concentrations were shown to be attainable in vivo in dogs and rhesus monkeys after intravenous exponential administrations of tracer. The results suggest that the approach developed employing exponential tracer infusion permits accurate measurement of myocardial perfusion and that it should prove useful in the noninvasive measurement of regional myocardial perfusion in vivo by positron emission tomography.
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