Deep learning has recently gained popularity achieving state-of-the-art performance in tasks involving text, sound, or image processing. Due to its outstanding performance, there have been efforts to apply it in more challenging scenarios, for example, 3D data processing. This article surveys methods applying deep learning on 3D data and provides a classification based on how they exploit them. From the results of the examined works, we conclude that systems employing 2D views of 3D data typically surpass voxel-based (3D) deep models, which however, can perform better with more layers and severe data augmentation. Therefore, larger-scale datasets and increased resolutions are required.

People with severe neurological impairments face many challenges in sensorimotor functions and communication with the environment; therefore they have increased demand for advanced, adaptive and personalized rehabilitation. During the last several decades, numerous studies have developed brain–computer interfaces (BCIs) with the goals ranging from providing means of communication to functional rehabilitation. Here we review the research on non-invasive, electroencephalography (EEG)-based BCI systems for communication and rehabilitation. We focus on the approaches intended to help severely paralyzed and locked-in patients regain communication using three different BCI modalities: slow cortical potentials, sensorimotor rhythms and P300 potentials, as operational mechanisms. We also review BCI systems for restoration of motor function in patients with spinal cord injury and chronic stroke. We discuss the advantages and limitations of these approaches and the challenges that need to be addressed in the future.

The increasing ageing global population is causing an upsurge in ailments related to old age, primarily dementia and Alzheimer’s disease, frailty, Parkinson’s, and cardiovascular disease, but also a general need for general eldercare as well as active and healthy ageing. In turn, there is a need for constant monitoring and assistance, intervention, and support, causing a considerable financial and human burden on individuals and their caregivers. Interconnected sensing technology, such as IoT wearables and devices, present a promising solution for objective, reliable, and remote monitoring, assessment, and support through ambient assisted living. This paper presents a review of such solutions including both earlier review studies and individual case studies, rapidly evolving in the last decade. In doing so, it examines and categorizes them according to common aspects of interest such as health focus, from specific ailments to general eldercare; IoT technologies, from wearables to smart home sensors; aims, from assessment to fall detection and indoor positioning to intervention; and experimental evaluation participants duration and outcome measures, from acceptability to accuracy. Statistics drawn from this categorization aim to outline the current state-of-the-art, as well as trends and effective practices for the future of effective, accessible, and acceptable eldercare with technology.

Brain-computer interfaces (BCIs) have been gaining momentum in making human-computer interaction more natural, especially for people with neuro-muscular disabilities. Among the existing solutions the systems relying on electroencephalograms (EEG) occupy the most prominent place due to their non-invasiveness. In this work, we provide a review of various existing techniques for the identification of motor imagery (MI) tasks. More specifically, we perform a comparison between Common Spatial Patterns (CSP) related features and features based on Power Spectral Density (PSD) techniques. Furthermore, for the identification of MI tasks, two well-known classifiers are used, the Linear Discriminant Analysis (LDA) and the Support Vector Machines (SVM). Our results confirm that PSD features demonstrate the most consistent robustness and effectiveness in extracting patterns for accurately discriminating between left and right MI tasks.

Intangible Cultural Heritage (ICH) is a relatively recent term coined to represent living cultural expressions and practices, which are recognised by communities as distinct aspects of identity. The safeguarding of ICH has become a topic of international concern primarily through the work of UNESCO (United Nations Educational, Scientific and Cultural Organisation). However, little research has been done on the role of new technologies in the preservation and transmission of intangible heritage. The chapter examines resources, projects and technologies providing access to ICH and identifies gaps and constraints. It draws on research conducted within the scope of the collaborative research project, i-Treasures. In so doing, it covers the state of the art in technologies that could be employed for access, capture and analysis of ICH in order to highlight how specific new technologies can contribute to the transmission and safeguarding of ICH.

Highlights • Network disorganization in people with SCD was found in the majority of the reported studies. • Brain Connectome in SCD is disrupted in a similar way as in MCI compared to HC. • Small-world and Rich-club were preserved in SCDs while aberrant local connections were observed.

These preliminary findings suggest that the amplitude of N170 elicited after negative facial stimuli could be modulated by the decline related to pathological cognitive aging and can contribute in distinguishing HC from SCI, MCI, and AD.

Background Functional decline in Alzheimer’s disease (AD) is typically measured using single-time point subjective rating scales, which rely on direct observation or (caregiver) recall. Remote monitoring technologies (RMTs), such as smartphone applications, wearables, and home-based sensors, can change these periodic subjective assessments to more frequent, or even continuous, objective monitoring. The aim of the RADAR-AD study is to assess the accuracy and validity of RMTs in measuring functional decline in a real-world environment across preclinical-to-moderate stages of AD compared to standard clinical rating scales. Methods This study includes three tiers. For the main study, we will include participants (n = 220) with preclinical AD, prodromal AD, mild-to-moderate AD, and healthy controls, classified by MMSE and CDR score, from clinical sites equally distributed over 13 European countries. Participants will undergo extensive neuropsychological testing and physical examination. The RMT assessments, performed over an 8-week period, include walk tests, financial management tasks, an augmented reality game, two activity trackers, and two smartphone applications installed on the participants’ phone. In the first sub-study, fixed sensors will be installed in the homes of a representative sub-sample of 40 participants. In the second sub-study, 10 participants will stay in a smart home for 1 week. The primary outcome of this study is the difference in functional domain profiles assessed using RMTs between the four study groups. The four participant groups will be compared for each RMT outcome measure separately. Each RMT outcome will be compared to a standard clinical test which measures the same functional or cognitive domain. Finally, multivariate prediction models will be developed. Data collection and privacy are important aspects of the project, which will be managed using the RADAR-base data platform running on specifically designed biomedical research computing infrastructure. Results First results are expected to be disseminated in 2022. Conclusion Our study is well placed to evaluate the clinical utility of RMT assessments. Leveraging modern-day technology may deliver new and improved methods for accurately monitoring functional decline in all stages of AD. It is greatly anticipated that these methods could lead to objective and real-life functional endpoints with increased sensitivity to pharmacological agent signal detection.