Objectives: The airway instrumentation of direct laryngoscopy and tracheal intubation is powerful noxious stimuli that should be attenuated by appropriate premedication, smooth induction, and rapid intubation. This study compared the efficacy intravenous dexmedetomidine and oral pregabalin premedication for attenuation of hemodynamic pressor response to laryngoscopy and intubation.Methods: A total of 60 patients of age group 20-50 years scheduled for elective surgeries under general anesthesia with American Society of Anesthesiologists physical Status I and II were divided into two groups each of 30. Group D received intravenous dexmedetomidine 1 mcg/kg over 10 minutes before induction, and Group P received oral pregabalin 150 mg 1 hr before intubation. Parameters observed were heart rate (HR) and mean arterial pressure (MAP) at baseline, after induction, immediately after intubation and then 5, 10, 15, and 30 minutes thereafter.Results: Attenuation of HR in group dexmedetomidine (78.12±10.0/minutes) immediately after intubation was statistically significant than group pregabalin (89.76±10.45/minutes). MAP significantly (p<0.05) decreased after intubation with dexmedetomidine. As compared to oral pregabalin, attenuation of HR and MAP was statistically significant till 30 minutes after intubation with intravenous dexmedetomidine.
Conclusion:Intravenous dexmedetomidine 1 µg/kg is more effective than oral pregabalin 150 mg in attenuating hemodynamic response to laryngoscopy and orotracheal intubation.
Objective: To know the prevalence of hypertension and diabetes mellitus among people seeking cataract surgery in the rural population. Study Design: Cross sectional study. Setting: Study was carried out at G.S.L.
To assess the hygiene practices among rural school children. SETTINGS AND DESIGN: This cross-sectional study was conducted at Government higher secondary school in rural area of Puducherry. METHODS AND MATERIAL: Around 214 children studying in standard 6 th to 8 th were randomly selected for the study during June to August 2011. The study was explained to the school children and their assent was taken before the study. They answered the pre-designed questionnaires. Data was collected by face to face interview. STATISTICAL ANALYSIS: Statistical analysis was done by using EPI INFO 3. RESULTS: Hygiene practice of hand washing before eating was 95.33%. Only 81.31% students used slippers/chappals during use of toilet. Around 58.41% of students went to open field for defecation and 6.07% of students did not wash their hands after defecation. Regarding the frequency of hygiene practice, only 62.15% and 68.22% of students brushed their teeth and bathed every day respectively. The study finding also showed that only 68.69% students washed their face twice daily where as 3.27% students washed their face weekly. As regards to the materials used for hygiene practice, 93.86% of students used tooth brush & paste for brushing of teeth, 85.98% of students used soap while taking bath and 25.70% of students did not use soap for hand wash after defecation. CONCLUSION: Study findings suggest the need for more hygiene practice education in rural schools. Such healthy practices may help to decrease the burden of communicable diseases in rural school settings.
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