Locally delivered SMV provides a comfortable and flexible method to improve clinical parameters and also to enhance bone formation.

The periodontal health status of individuals with AD deteriorates with disease progression and was closely related to their cognitive function.

There is a need for dental care and encouragement to use plaque control methods for subjects with PKD as periodontal pathology presented a high prevalence even in the early stages of PKD.

Azithromycin was found to significantly improve the clinical and microbiological parameters in AAAP individuals.

PRF + 1.2% ATV showed similar improvements in clinical parameters with a greater percentage radiographic defect depth reduction compared with PRF alone in treatment of IBDs in individuals with CP. Thus, 1.2% ATV failed to augment the regenerative potential of PRF alone in periodontal IBDs.