This study was undertaken to determine the association of the personal factors of culture, attitude and motivation on health behavior among Malaysian adolescents. A cluster sampling technique was used and a total of 1,029 students with ages ranging from 15 to 17 years (M age = 15.9, SD = .637) were selected as respondents. The research instrument was a self-administered questionnaire covering health behavior, culture, attitude, and motivation towards health. The strongest linear relationship was found between culture and health behavior (r = .618, p = .001). Besides the culture of adolescents being the main predictor of health behavior (β = .365, p = .000), attitude (β = .283, p = .000) and motivation (β = .064, p = .033) also had significant independent effects on health behavior. Hence, culture, attitude and motivation should be taken into consideration in the promotion of health education, especially at school level. Background of the study Health behavior is a common term in health psychology and can be understood simply as behavior that influences health. Research into adolescents' health behavior and the personal factors that influence them is essential for the development of effective health education and the observation of good health. It is important that young people's health is considered in its broadest sense to encompass social, physical, and emotional well-being. Furthermore, in line with the World Health Organization's (WHO) perspective, health is viewed as a resource for everyday living, not just the absence of disease. Many behavioral patterns that reflect young people's lifestyles may directly or indirectly impact on their health in the short or long term. Certain behavior is shaped during adolescence, while some patterns of behavior, such as eating habits, become established in childhood. Taking selected personal factors as predictors to health behavior, the present study analyzed psychological, social, and environmental influences that contribute to adolescent health. According to the Youth Malaysia Index reported by Ministry of Youth and Sports, Malaysia, the level of health among the youth in Malaysia, at 65.8%, is moderate (Ministry Youth & Sport Malaysia, 2015), pointing to the need for improvement to their health behavior. Many lifelong habits that mold health behavior are formed during childhood and adolescence (Bandura, 1998). With regard to the adolescent's transition from children into adulthood, aspects of culture, motivation, and altitude may affect their future well-being. During this transition, those who have poor health habits may drop them and ARTICLE HISTORY