The malignant variant of epithelioid angiomyolipoma (EAML) of the kidney is uncommon, extremely aggressive and behaves like a renal cell carcinoma. We present a case of a 12-year-old male with malignant EAML who was treated according to adult treatment protocols. To our knowledge, axitinib has not been used before in children. We conclude that adult protocols, in this rare case, could be safely used in rare childhood malignancies.
ACAR, Z.; DEGER, U.; GÖRKEM, Ü; TOGRUL, C.; DEVECI, E.; KAYA, S. & EKINCI, A. Effects of Potentilla fulgens on tuba uterina in ovariectomized rats. Int. J. Morphol., 34(2):460-464, 2016.
SUMMARY:A total of 32 Wistar rats were divided into four equal groups: (I) sham, (II) ischemia, (III) reperfusion and (IV) Potentilla fulgens. In groups I and II, ovary torsion was not performed and no drug was administered. In group III, 1 h of ischemia and 2 h of reperfusion were performed and no drug was given. Group IV received 400 mg/kg/day Potentilla fulgens intraperitoneally 5 days before Ischemia-reperfusion. All the parameters were observed to be significantly decreased (P<0.05) in all the experimental groups compared to the control group. In the sections of the ischemia-reperfusion group, degeneration of epithelium, dilation of blood vessels were observed. Potentilla fulgens administration reduced the morphological changes by induced I/R; in particular, infiltration, hemorrhage and vascular dilatation were decreased. Potentilla fulgens application during torsion, it plays an important role in maintaining the epithelial structure with E-cadherin expression. We suggest that PECAM-1(CD31) are a regulator of the microvascular response of the tubal mucosa.
Pancreatic involvement of non-Hodgkin's lymphoma is extremely rare in childhood and can be overlooked in differential diagnosis of pancreatic masses. In this report we described a 10-year-old boy who presented with pancreatitis and obstructive jaundice, which was the result of pancreatic involvement of Burkitt lymphoma.
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