No abstract

No abstract

No abstract

O presente trabalho relata duas infecções naturais por Trypanosoma evansi em cães, que vieram a óbito no município de Uruguaiana, RS. Os animais oriundos da zona rural foram recebidos no hospital veterinário da Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS), em diferentes datas, apresentando apatia, febre e aumento dos linfonodos submandibulares. No esfregaço sangüíneo, foram identificadas formas flageladas pertencentes à espécie T. evansi. A verificação desses casos serve de alerta aos proprietários de animais e médicos veterinários para a presença da doença na região e salienta a necessidade de maiores investigações na epidemiologia da parasitose e criação de medidas profiláticas que evitem novas infecções.

This study aimed to assess the plasma lipid peroxidation and the susceptibility of erythrocytes to in vitro peroxidation as indicators of oxidative damage in erythrocytes and their roles in the pathogenesis of anemia during the early acute phase of Trypanosoma evansi infection in rats. Fifty male Wistar rats were randomly distributed into seven groups: three trypanosome-infected groups (T(2), T(4) and T(6); n=10 animals per group) and four uninfected controls (C(0), C(2), C(4) and C(6); n=5 animals per group). Animals from trypanosome-infected groups were inoculated intraperitoneally with 10(6) trypanosomes. Blood samples were collected by cardiac puncture before infection (day 0; group C(0)) or on the 2nd (C(2) and T(2)), 4th (C(4) and T(4)) and 6th (C(6) and T(6)) day post-infection (dpi). Samples were analyzed for red blood cell (RBC) count, hemoglobin (Hb) concentration, packed cell volume (PCV), plasma malondialdehyde (MDA) and in vitro peroxidation of erythrocytes. The mean values of the hematological indices gradually decreased in the infected rats compared with the control. MDA was significantly increased (P<0.001) on the 6th dpi in infected versus control animals and was negatively correlated with PCV (P<0.001; R(2)=0.372). The values for erythrocyte in vitro peroxidation were higher for groups T(4) and T(6) than for the control rats (P<0.01). A positive correlation between erythrocyte peroxidation and MDA (P<0.001; R(2)=0.414) was observed. The results of this study indicate that T. evansi infection in rats is associated with oxidative stress, indicated by lipid peroxidation and oxidative damage in erythrocyte membranes, as demonstrated by in vitro peroxidation. This may be one of the causes of anemia in acute trypanosomosis.

Primeiro registro de

No abstract

A meta-analysis was carried out in order to study the effects of endoparasites on the performance of growing pigs. Criteria that should be considered for the publication selection were: (1) the health challenge caused by parasites; (2) pig in growing phase; (3) presentation of the nutritional composition of the diets and (4) animal performance. Meta-analysis followed three sequential analysis: graphical, correlation and variance-covariance. The group that were infected with parasites had an average daily feed intake 5% lower than that the control group (2044 vs. 2147 g d(-1); P<0.001), their average daily weight gain was also 31% lower (665 vs. 987 g d(-1); P<0.001) and their feed conversion ratio was 17% superior than that of the control group (3.07 vs. 2.62; P<0.001). The variance decomposition demonstrated that 59% of the reduction in weight gain was explained by the reduction in their feed intake, as well as a 6% reduction being due to parasites.