The current study aimed to investigate the inhibitory activity of aqueous extracts of different plant parts of Rosa damascena, represented by the whole rose, petals, and calyces, against clinical isolates of Staphylococcus spp., Escherichia coli, and Klebsiella pneumoniae, and the inhibition of the bacterial cell. The isolates were obtained from the advanced microbiology laboratory for postgraduate studies in the Department of Biology, Faculty of Education for Girls. They were isolated from urinary tract infections, which were subsequently subjected to diagnosis by the Vitek-2 compact system to confirm the type of bacteria as well as their sensitivity to antibiotics. The results obtained included Staphylococcus aureus, Staphylococcus haemolyticus, Staphylococcus lentus, Staphylococcus saprophyticus, E. coli, and K. pneumoniae. A test was conducted to investigate the microbiological inhibitory activity of aqueous plant extracts of the whole rose, petals, and calyces using the well diffusion method and three concentrations of each aqueous extract (25, 50, and 100 mg/ml). The results showed the inhibitory ability of all concentrations of the different extracts toward Staphylococcus spp., and E. coli and K. pneumoniae bacteria were not affected by the different concentrations of the plant extract. The concentration of (100 mg/ml) for the aqueous extract was the most efficient in inhibiting growth compared to the other concentrations. The synergistic effect of three antibiotics was examined (Amoxicillin-clavulanate 10/20 μg, Piperacillin 100 μg, Trimethoprimsulfamethoxazole 23.75/1.25 μg) and for all concentrations of the aqueous plant extract was investigated in both E. coli and K. pneumoniae, as it found a synergistic action between some of the antibiotics and extracts towards inhibiting the growth of the two bacterial isolates Resistance to the plant extract alone. Bacterial isolates showed a significant decrease in the rate of adhesion to epithelial cells isolated from urine samples of healthy women in the presence of the aqueous extract of whole rose, petals, and calyces at their three concentrations compared with the control treatment.
Acute respiratory illness could be caused by Human parainfluenza viruses (PIVs) in children, the old, and immunocompromised patients. The frequent and common cause of pneumonia and bronchiolitis is PIV3, whilst the upper respiratory tract illness and croup are frequently caused by PIV1 and PIV2. However, this study aimed to highlight a group of patients with type III influenza virus. 29 sample took from people suffering from upper and lower respiratory diseases as well as 27 conrol sample to assessing the level of a type of cellular motility in their catheter, cimclin cxcl10 by the use of ELISA. The study also showed that there were no significant differences between Male Injury Rate Now as well as an inverse relationship between the level of cimokin cxcl10 and age. Moreovere, this study showed an increase in the level of cimcin cxcl10 in the case of HPIV infection compared with the control group.
Periodontitis is a microbially driven inflammatory conditions of the gingiva causing destruction of the ligaments and alveolar bone supporting the teeth resulting in oral malodor and tooth loss. The aim of the present research was to estimate the serum level of TGF-β1 in patients with periodontitis compared with healthy individual and to assess the relationship between the TGF-β1serum and the Immunoglobulin(IgG). A total of 60 patients were included in this research and 20 individuals was healthy group. Serum samples separated from the whole blood of patients and healthy. Level of TGF-β1 was determined by an enzyme linked immunosorbent assay. The results showed statistically significant elevation in level of TGF-β1 in patients than in healthy group and there was a significant correlation between the levels of TGF-β1 and immunoglobulin IgG in patients with periodontitis.
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