L'indice d'adiposité viscérale (IAV) -marqueur potentiel du risque cardio-métabolique L'importance du risque cardiovasculaire/cardio-métabolique est particulière car le contrôle de ses composantes peut affecter l'athérogenèse et ses conséquences cliniques: la cardiopathie ischémique, la maladie cérébrovasculaire, l'artériopathie périphérique et le diabète sucré (DS). Pour évaluer le risque cardio-métabolique associé à l'obésité viscérale, on a essayé d'identifier un indicateur utile dans la pratique clinique. L'indice d'adiposité viscérale (IAV) pourrait devenir un outil facile à utiliser dans la pratique quotidienne qui met en évidence le risque cardio-métabolique. IAV indique la fonction du tissu adipeux viscéral et sa croissance est indépendamment corrélée aux risques cardiovasculaire et cérébrovasculaire. Le monde médical a essayé d'identifier un moyen facile d'évaluer le risque cardiovasculaire, de sorte que l'indice d'adiposité viscérale, dont la formule inclut un certain nombre de facteurs de risque cardiovasculaires, ait été introduit.
Background and Aims: Studies have shown an increased incidence of chronic complications in people with type 1 diabetes mellitus (T1DM) with insulin resistance (IR) compared to people with T1DM without IR. Estimated glucose disposal rate (eGDR) is an important indicator of IR in patients with T1DM, lower eGDR levels indicating greater IR. It was shown that T1DM patients with chronic complications (diabetic retinopathy - DR, diabetic peripheral neuropathy - DPN or diabetic kidney disease - DKD) exhibit higher IR compared to patients without chronic complications. The aim of our study was to evaluate eGDR as a marker for the assessment of IR in T1DM patients.Materials and Methods: The study was observational, cross-sectional and included 140 T1DM patients with diabetes duration>10 years. The collected data were analyzed using the Statistic Package for Social Sciences (SPSS) version 22 software (IBM Corporation, Armonk, NY, USA).Results: eGDR presented statistically significant correlations (p<0.05) with the presence of metabolic syndrome (MS), obesity, chronic complications of T1DM, cardiovascular risk (CVR) and smoking status in patients with T1DM duration >10 years.Conclusions: eGDR represents a reliable marker for assessing the IR in T1DM.
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