Visceral Adiposity Index (Vai) – A Potential Marker of Cardiometabolic Risk

Gârgavu, Sigina R.; Clenciu, Diana; Roșu, Maria M.; Cojan, Tiberiu Ștefăniță Țenea; Costache, Andrei; Vladu, Ionela Mihaela; Mota, Maria Paula

doi:10.31688/abmu.2018.53.2.11

Cited by 9 publications

(13 citation statements)

References 39 publications

(44 reference statements)

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“…The classification of overweight or obesity according to the body mass index (BMI) has been commonly employed, even though other scales, such as waist circumference (WC), waist to height ratio (WtHR), and University of Navarra Clinic-Body Fat Estimator (CUN-BAE) are emerging to be considered as novel indicators in clinical research for the diagnosis of obesity [ 5 ]. Other indicators, such as Equation Córdoba for Estimation of Body Fat (ECORE-BF), relative fat mass (RFM), Palafolls formula, Deurenberg fat mass index, body roundness index (BRI), body shape index (ABSI), visceral adiposity index (VAI) [ 6 ], conicity index, normalized weight-adjusted index (NWAI), body surface index (BSI), body surfaces area (BSA), or body fat index (BFI), are used for stratification into the different categories of overweight and obesity, according to gender differences in body composition.…”

Section: Introductionmentioning

confidence: 99%

Relationship between Atherogenic Dyslipidaemia and Lipid Triad with Different Scales of Overweight and Obesity in 418,343 Spanish Workers

Busquets-Cortés¹,

López²,

Paublini³

et al. 2022

Journal of Nutrition and Metabolism

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Obesity induces alterations in lipid biochemistry, evolving toward dyslipidaemia atherogenesis, a critical factor in the development of cardiovascular events. Two relevant forms of lipid abnormalities are atherogenic dyslipidaemia (AD) and lipid triad (LT), which involve alterations in triglyceride levels, HDL-c, and LDL-c. The aim of this study was to assess the linkage of atherogenic AD and LT with different scales of overweight and obesity. We carried out a cross-sectional study including 418,343 Spanish adult workers, recruited from workplace health assessments. Atherogenic dyslipidaemia was defined as triglyceride levels ≥ 150 mg/dL, HDL values < 40 mg/dL in men and <45 mg/dL in women, and normal LDL. Additionally, if LDL levels were >160 mg/dL, LT was considered. Subjects affected by AD and LT in the study exhibited significantly higher mean values than those without AD and LT in all overweight, obesity, and body fat related scales studied. VAI (visceral adiposity index) was the strongest predictor of AD (AUC = 0.934, 95% CI: 0.933 to 0.936) and LT (AUC = 0.926, 95% CI: 0.923 to 0.928). Atherogenic dyslipidaemia and LT positively correlate with different scales of overweight and obesity. Further studies should aim to identify other contributory factors. Our obtained data might be useful in laying the groundwork for future works on AD and LT.

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Section: Introductionmentioning

confidence: 99%

Relationship between Atherogenic Dyslipidaemia and Lipid Triad with Different Scales of Overweight and Obesity in 418,343 Spanish Workers

Busquets-Cortés¹,

López²,

Paublini³

et al. 2022

Journal of Nutrition and Metabolism

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“…10 VAI is a mathematical formula that consists of laboratory parameters and the core elements of anthropometry such as BMI and WC, TGs, and HDL-C. 11 Sigina et al suggested that VAI can be considered as a potential tool for assessing cardiometabolic risk. 12 There is a significant association of VAI with the different components of metabolic syndrome in older men and women including hyperglycemia, hypertriglyceridemia, low HDL-cholesterol, and abdominal obesity. 13 Previous study revealed that VAI can provide an estimation of subclinical atherosclerosis than the calculation of Homeostatic Model Assessment of Insulin resistance (HOMA-IR) in individuals prone to T2DM.…”

Section: Introductionmentioning

confidence: 99%

Visceral Adiposity Index: A Simple Tool for Assessing Risk of Type 2 Diabetes Mellitus

Zar

Ali

2022

J Ayub Med Coll Abbottabad

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Background: The prevalence of type 2 diabetes mellitus (T2DM) has increased recently in Pakistan. Visceral adiposity index (VAI) appears to be a better predictor for metabolic syndrome associated with insulin resistance. VAI has been shown to be linearly and positively associated with diabetes mellitus (DM) in many populations. It is, however, uncertain whether VAI could be associated with T2DM in the Pakistani adult population. Methods: This is a cross-sectional study of 300 outpatients with a newly diagnosed T2DM. Subjects were recruited from Lady Reading Hospital, Pakistan, during the period from April, 2020 to January, 2021. For all study subjects, anthropometric measurements were performed. Blood samples were collected for the assessment of high-density lipoproteins (HDL-C), triglycerides (TGs), glycated hemoglobin (HbA1c), and random blood glucose. Results: Participants with high VAI showed poor glycemic control. The number of patients with poor glycemic control increased across the VAI quartiles. VAI showed significant correlations with TGs (r=0.715, p=<0.001), total cholesterol (TC) (r=0.256, p=<0.001), low density lipoprotein (LDL-C) (r=0.154, p=0.007), uric acid (r=0.205, p=0.019), duration of diabetes (r=0.171, p=0.033), TSH (r=0.163, p=0.007), and random blood glucose (r=0.195, p=0.019). Conclusion: Our data suggest that VAI is significantly and positively correlated with the risk factors of DM such as random blood glucose, uric acid and TSH. The findings of the study do not imply a significant direct association between VAI and DM among the Pakistani adult population. Prospective-large scale studies can help inform an effectiveness of VAI for the prediction of the risk of T2DM among Pakistani population.

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“…Visceral adiposity index and LAP levels are very efficient in predicting cardiovascular disease risk factors in various clinical studies (20)(21)(22)(29)(30)(31). In people with T2DM and visceral obesity, lipid and lipoprotein metabolism problems are common, resulting in diabetic dyslipidemia and a high risk of cardiovascular disease.…”

Section: Discussionmentioning

confidence: 99%

Tip 2 Diyabetli Bireylerde Aterojenik Plazma İndeksi ile İlişkili Visseral Adipozite İndekslerinin Değerlendirilmesi

Yılmaz

Özçıçek

Mertoğlu

et al. 2022

Düzce Tıp Fakültesi Dergisi

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Aim: This study was aimed to investigate visceral adiposity indicators and the atherogenic index of plasma (AIP) in type 2 diabetes mellitus (T2DM) patients. Material and Methods: A total of 353 adults aged between 18 and 74 years were included in this study. Bodyweight, height, waist, and hip circumference were measured; fasting blood glucose, HbA1c, and lipid profile (total cholesterol, triglyceride, low-density lipoprotein cholesterol, and high-density lipoprotein cholesterol) values were analyzed. Visceral adiposity index (VAI), lipid accumulation product (LAP), body adiposity index (BAI), body shape index (ABSI), body roundness index (BRI), conicity index (CI), and AIP levels were calculated. Results:The study included 116 (32.9%) males and 237 (67.1%) females, with a mean age of 57.8±11.5 years. AIP z-scores were found to be directly related to T2DM (OR, 5.03; 95% CI: 1.95-13.01), while VAI z-scores were less associated with T2DM (OR, 1.10; 95% CI: 1.03-1.18). According to the ROC curve analysis, although the area under the curve (AUC) is weak to distinguish diabetic patients with VAI, LAP, and AIP, it is statistically significant (p<0.

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Visceral Adiposity Index (Vai) – A Potential Marker of Cardiometabolic Risk

Cited by 9 publications

References 39 publications

Relationship between Atherogenic Dyslipidaemia and Lipid Triad with Different Scales of Overweight and Obesity in 418,343 Spanish Workers

Relationship between Atherogenic Dyslipidaemia and Lipid Triad with Different Scales of Overweight and Obesity in 418,343 Spanish Workers

Visceral Adiposity Index: A Simple Tool for Assessing Risk of Type 2 Diabetes Mellitus

Tip 2 Diyabetli Bireylerde Aterojenik Plazma İndeksi ile İlişkili Visseral Adipozite İndekslerinin Değerlendirilmesi

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