With a prevalence of 63.6% [8] and 39.1% [9] studies have shown that Road Traffic Accidents (RTAs) are the most common determinant of traumatic orthopedic injuries. RTAs are the most common determinant of fractures, with a prevalence of 29.4%, [10]
This case study deals with a 32-year-old Indian male patient who presented with a traumatic head injury in the hospital, experienced uncontrolled bleeding after conducting surgery, and was eventually diagnosed with Glanzmann thrombasthenia. Glanzmann thrombasthenia is a rare hereditary blood clotting disorder characterised by a lack of platelet aggregation due to the absence of platelet glycoprotein IIb/IIIa. This occurrence is generally triggered by consanguineous marriages and is apparent in approximately one in one million people. Education and raising awareness about consanguinity in communities may help to reduce challenging, unusual genetic diseases.
The present work was aimed that the two Ruthenium compounds namely, [Ru(A) 2 (B)]Cl 2 , where A = 1,10-phenanthroline; B = 2-NO 2 -phenyl thiosemicarbazone (Compound R 1 )/2-OH-phenyl thiosemicarbazone (Compound R 2 ) have been tested for antibacterial activity at the concentrations of 1 mg/mL against various Gram-Positive organisms (Lactobacillus, Staphylococcus pyrogenes, Bacillus subtilis, Staphylococcus aureus & Bacillus megatarium) and Gram-Negative organisms (Pseudomonas aeruginosa, Escherichia coli, Proteus vulgaris, Enterobacter aerogenes, Salmonella paratyphi, Klebsiella pneumonia & Proteus mirabilis). The compounds were also tested for antifungal activity against Aspergillus clavatus, Aspergillus niger, Colletotrichum & Penicillium notatum by using agar diffusion assay and antimalarial activity against Plasmodium falciparum (Strain 3D7) using MTT assay. The results concluded that the compound R 1 exhibited significant antibacterial activity than R 2 against Gram-Negative bacteria with zones of inhibition ranging from 15-20 mm. and mild antibacterial activity against Gram-Positive bacteria in comparison to tetracycline, streptomycin and rifampicin. These complexes were found to have moderate antifungal activity with no activity was however observed against Aspergillus niger. The compound, R 1 exhibited antimalarial activity at 10 µg/mL, whereas R 2 did not show antimalarial activity upto 50 µg/mL. Sensitivity to the compounds was greatest in the gram-negative bacteria, followed by the grampositive bacteria and fungi.
Objective: The objective of the study was to study the prevalence of various skin diseases in pediatric population.
Methods: A prospective observational study was conducted at private children’s outpatient clinic in Warangal from March to August 2018 with the prior approval from the Institutional Ethical Committee BIPS/IEC/2018/P8. A total of 200 patients with various skin diseases of age group <17 years were included in the study.
Results: Out of 200 pediatric skin disorders, male children 138 (69%) outnumbered female children 62 (31%). The mean age of the study population was found to be 5.85±4.11 years. About 64% of the patients are from rural area and 36% are from urban. The percentage of skin disorders is allergic infections (26%), bacterial infections (23%), viral infections (11%), fungal infections (7.5%), parasitic infections (6%), autoimmune disorders (4%), and skin adnexa (2.5%).
Conclusion: Our study concludes that the prevalence of allergic and bacterial skin infections was found to be common among male children from rural area
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