Background: Stroke causes weak functional mobility in survivors and affects the ability to perform activities of daily living. Wearable ankle robots are a potential intervention for gait rehabilitation post-stroke. Objective: The aim of this study is to provide a systematic review of wearable ankle robots, focusing on the overview, classification and comparison of actuators, gait event detection, control strategies, and performance evaluation. Method: Only English-language studies published from December 1995 to July 2018 were searched in the following databases: PubMed, EMBASE, Web of Science, Scopus, IEEE Xplore, Science Direct, SAGE journals. Result: A total of 48 articles were selected and 97 stroke survivors participated in these trials. Findings showed that few comparative trials were conducted among different actuators or control strategies. Moreover, mixed sensing technology which combines kinematic with kinetic information was effective in detecting motion intention of stroke survivors. Furthermore, all the selected clinical studies showed an improvement in the peak dorsiflexion degree of the swing phase, propulsion on the paretic side during push-off, and further enhanced walking speed after a period of robot-assisted ankle rehabilitation training. Conclusions: Preliminary findings suggest that wearable ankle robots have certain clinical benefits for the treatment of hemiplegic gait post-stroke. In the near future, a multicenter randomized controlled clinical trial is extremely necessary to enhance the clinical effectiveness of wearable ankle robots.

Using neuroimaging techniques to explore the central mechanism of acupuncture gains increasing attention, but the quality control of acupuncture-neuroimaging study remains to be improved. We searched the PubMed Database during 1995 to 2014. The original English articles with neuroimaging scan performed on human beings were included. The data involved quality control including the author, sample size, characteristics of the participant, neuroimaging technology, and acupuncture intervention were extracted and analyzed. The rigorous inclusion and exclusion criteria are important guaranty for the participants' homogeneity. The standard operation process of acupuncture and the stricter requirement for acupuncturist play significant role in quality control. More attention should be paid to the quality control in future studies to improve the reproducibility and reliability of the acupuncture-neuroimaging studies.

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Background:Short-stem total hip arthroplasty (SHA) has been increasingly used in the treatment of hip arthroplasty. However, it is unclear whether there is a superiority of SHA in periprosthetic bone remodeling over standard stem total hip arthroplasty (THA). This meta-analysis of randomized-controlled trials (RCTs) compared the periprosthetic bone remodeling after SHA and THA.Methods:PubMed and Embase were screened for relevant publications up to May 2017. RCTs that compared periprosthetic bone remodeling with bone mineral density (BMD) changes between SHA and THA were included. Meta-analysis was conducted to calculate weighted mean differences (WMDs) and 95% confidence intervals (CIs) using Stata version 12.0. Quality appraisal was performed by 2 independent reviewers using RevMan 5.3 software and Grades of Recommendation Assessment, Development, and Evaluation criteria.Results:Seven studies involving 910 patients and 5 SHA designs (Proxima, Fitmore, Microplasty short, Unique custom, and Omnifit-HA 1017) were included for meta-analysis. The pooled data showed no significant differences in the percentage BMD changes in all Gruen zones, with Gruen zone 1 [mean difference (MD) = 11.33, 95% CI, −1.67 to 24.33; P = .09] and Gruen zone 7 (MD = 8.46, 95% CI, −1.73 to 18.65; P = .10). Subgroup analysis of short SHA stems with lateral flare showed a significant less percentage BMD changes compared with standard THA in Gruen zone 1 (MD = 27.57, 95% CI, 18.03–37.12; P < .0001) and Gruen zone 7 (MD = 18.54, 95% CI, 8.27–28.81; P < .0001).Conclusion:The study shows moderate-quality evidence that periprosthetic bone remodeling around the analyzed SHA stems was similar to standard THA stems. However, short SHA stems with lateral flare revealed a moderate- to low-quality evidence for superiority over the standard THA and highlighted the importance of the different SHA designs. Besides, it has to be noticed that despite a similar pattern of periprosthetic bone remodeling, the femoral length where periprosthetic bone remodeling occurs is clearly shorter in SHA. Due to the moderate- to low-quality evidence and the limited stem designs analyzed, the further large-scale multicenter RCTs including the most recent SHA designs are required. However, the current findings should be considered by surgeons for counseling patients regarding total hip replacement.

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