Mucormycosis is a rare opportunistic infection caused by fungus belonging to the order Mucorales. A case of a controlled diabetic male with rhino maxillary mucormycosis, with cerebral extension, is described. The patient presented with hemifacial swelling, a nasal twang in his voice, fever, ocular signs, gross tissue destruction, and was sluggish. Early recognition of mucormycosis is necessary to limit the spread of infection, which can lead to high morbidity and mortality. Therefore, health practitioners should be familiar with the signs and symptoms of the disease.
Opportunistic subcutaneous fungal infections are increasing in present times due to increasing incidence of many medical conditions causing immunosupression like diabetes, AIDS, organ transplant recipients and anticancer therapy. Pyrenochaeta romeroi, a fungus from the dematiaceae group, first described by Borelli in 1959, is saprophyte to soil and plants.We present a rare case of subcutaneous phaeohyphomycotic cyst in a diabetic female caused by P. romeroi.
The present research was taken up with broad objective to study the marital adjustment, mental health and frustration reactions males and females of middle age from Delhi, India. The sample comprised of 150 males and 150 females (n=300) which are bank employees, doctors and lecturers, within the age range of 40-55 years from Delhi, India. It was seen that Females showed high level of recreational adjustment as compared to males but males were having better group oriented attitude than females.
Aim: Health-care associated infections (HAIs) affect 5-20% of patients admitted in the hospitals. Catheterassociated urinary tract infections (CAUTI) are the commonest HAIs accounting for about 35-45% of these nosocomial infections due to lack of aseptic procedures and prolonged catheterization. The spectrum and antimicrobial resistance pattern of micro-organism that cause CAUTIs vary among institutions and can change from year to year. Materials and Methods: A retrograde analysis was performed on patients with indwelling catheters admitted in medical and surgical ICU. The patient's demographic details (name, age,sex), date of hospital admission, provisional diagnosis, treatment details, time and date of catheter insertion and removal were recorded as per CDC criteria. CAUTI was diagnosed as per CDC guidelines. Results and Conclusions: A total of 687 patients were catheterized in ICU for an aggregate of 2748 patient days. The device utilization rate was 0.66. The prevalence of CAUTI per 1000 device days was 8.73.The causative uropathogens included Candida, E.coli, Enterococcus spp. A high degree of resistance was observed in all the isolates. There is a need to introduce appropriate measures aimed at proper use of catheters, to organise more frequent suitable personnel training and emphasis on hand washing procedures.
Background:Response to treatment of a manic episode is dependent on several sociodemographic and clinical factors as reported by researchers from other countries. The prescription of mood stabilizers and/or antipsychotics for manic episode depends on these factors. There is a lack of availability of data from India on this topic. Hence, this study was planned to identify the predictors of pharmacological response.Materials and Methods:Forty-two patients with a diagnosis of bipolar affective disorder current episode manic were enrolled and assessed for sociodemographic variables and clinical variables such as age of onset, family history, comorbidities, index episode, and number of past episodes. They were divided into four groups depending on the treatment they were receiving, namely, lithium with an antipsychotic (n = 25), lithium with divalproex and an antipsychotic (n = 8), divalproex with an antipsychotic (n = 5), and the miscellaneous group (n = 4). The primary outcome measure was improvement in the Young Mania Rating Scale score and secondary outcome measure was duration of ward stay.Results:There was a significant improvement in all the treatment modalities and it was comparable. There was no significant impact of any sociodemographic or clinical variable on treatment outcome except that females had significantly better response than males. There was nearly significant shorter duration of hospitalization in the lithium and antipsychotics groups compared to divalproex group.Conclusion:All treatment modalities are equally efficacious in the management of manic episode in short term. However, lithium and antipsychotics tend to produce early response than divalproex. Other sociodemographic and clinical predictors were not significantly associated with response.
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