We report our experience of using double or multiple looped sutures for primary tenorrhaphy combined with early active mobilization. In 46 patients involving 51 fingers with flexor tendon lacerations, double threads of the looped nylon suture were placed to repair injured FDP or FDS tendons, or three threads of looped nylon suture were made to repair the FDP tendons. Using White's (1956) criteria, the results were good or excellent in 76.5% of fingers. The double and multiple looped sutures are of sufficient strength to sustain early motion, and cause little disturbance in the circulation. Satisfactory function following primary tendon repair can be expected with these new techniques.
A considerable proportion of patients who appear to have resectable NSCLC might be regarded as having systemic disease, which is often undetectable by current tumour staging method. In terms of a marker used for the NSCLC patients who undergo operation, CEA is more suitable than CK19. The CK19-expressing epithelial cells are released intraoperatively into the circulation, meanwhile CEA-expressing tumour cells are disseminated mostly postoperatively. Surgical manipulation could promote the release of tumour cells into the bloodstream, but the ligation of pulmonary vein before the ligation of the pulmonary artery may partly prevent such release during surgery.
A tremendous amount of research has been dedicated to laying the groundwork that will eventually lead to successful limb transplantation in humans. Limb transplantation in animal models has also been widely used for evaluating composite tissue allografts and various immunosuppressive regimens. Currently, there is no mouse model of limb transplantation. Such a model is attractive because it would allow investigators to apply the well-defined genetic characteristics of the mouse to the challenging field of limb transplantation. In this study, 12 mice underwent orthotopic hind limb transplantations using end-to-end anastomoses of the femoral vessels. The success rate of this surgical procedure was 83%, with 10 of the 12 limbs surviving. Experimental devices, operative procedures, and the major elements of success are discussed.
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