The adjunctive use of 400 or 250 mg of MTZ plus 500 mg of AMX/TID/14 days offers statistically significant and clinically relevant benefits over those achieved with SRP alone in the treatment of severe GChP. The added benefits of the 7-days regimen in this population were less evident. (ClinicalTrials.gov NCT02735395).

Results of this systematic review suggest moderate evidence supporting association of Porphyromonas gingivalis, Treponema denticola, and Tannerella forsythia and some evidence supporting association of Prevotella intermedia and Campylobacter rectus with the etiology of peri-implantitis.

Although a high success rate has been reported for the bone allograft survival, this systematic review demonstrated low level of scientific evidence articles with short follow-up time and diversified methodology with difficult possibilities to compare their results.

The aim of this observational study was to assess the degree of patient satisfaction toward implant-supported prostheses. A questionnaire was used with two scales (one consisting of detailed adjectival and the other of numerical responses) regarding chewing, esthetics, speaking, comfort and overall satisfaction. The scales were administered to a sample of 147 patients treated with implants and prostheses. The data were submitted to the Kappa statistic and the Chi-square test to analyze the association between dependent and independent variables. High degrees of satisfaction (greater than 91%) were found for all categories evaluated, regardless of gender, age, number of implants or type of prosthesis. "Comfort" was associated significantly with the number of implants (p = 0.038), and "speaking" was associated significantly with the type of prosthesis (p = 0.029). Positive agreement was found between the scales for all categories evaluated, without statistically significant differences regarding respondent preference (p = 0.735). Patients treated with implant-supported prostheses were highly satisfied with the treatment.

Background: The 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions grouped the diseases previously recognized as chronic (CP) or aggressive (AgP) periodontitis under a single category named periodontitis. The rationale for this decision was the lack of specific patterns of immuneinflammatory response or microbial profiles associated with CP or AgP. However, no previous studies have compiled the results of all studies comparing subgingival microbial data between these clinical conditions. Thus, this systematic review aimed to answer the following focused question: "Do patients with AgP periodontitis present differences in the subgingival microbiota when compared with patients with CP?" Methods: A systematic review was conducted according to the PRISMA statement. The MEDLINE, EMBASE, and Cochrane databases were searched up to June 2019 for studies of any design (except case reports, case series, and reviews) comparing subgingival microbial data from patients with CP and AgP. Results: A total of 488 articles were identified and 56 were included. Thirteen studies found Aggregatibacter actinomycetemcomitans elevated in AgP in comparison with CP, while Fusobacterium nucleatum, Parvimonas micra, and Campylobacter rectus were elevated in AgP in a few studies. None of these species were elevated in CP. However, the number of studies not showing statistically significant differences between CP and AgP was always higher than that of studies showing differences. Conclusion: These results suggested an association of A. actinomycetemcomitans with AgP, but neither this species nor the other species studied to date were unique to or could differentiate between CP and AgP (PROSPERO #CRD42016039385).

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The improvement in clinical attachment level achieved by regenerative techniques with biomaterials demonstrated satisfactory results over the long-term. However, regenerative techniques still present different success rates with regard to gain in clinical attachment level.

AIM: To evaluate the microshear bond strength of 4 dental adhesive systems after 1 year-water storage. MATERIAL AND METHODS: The sample consisted of 120 cylinders of composite, obtained from 24 bovine incisors, which were divided into four experimental groups: G1-Scotchbond Multi-Purpose, G2-Single Bond 2, G3-Clearfil SE Bond, G4-Adper Easy One and two storage times in distilled water: T0 - 24h and T1 - 1 year. A bivariate analysis was performed using the ANOVA and Tukey test (α=0.05). Results were evaluated inter-and intra-group in both times. RESULTS: After 24 hours, G1T0 (39.68A ± 11.55) showed higher bond strength (MPa) followed by G2T0 (22.71B ± 4.07), G3T0 (18.94BC ± 7.29) and G4T0 (13.30C ± 3.94). After 1 year of storage only G1T1 (33.95A ± 6.35) and G3T1 (13.59BC ± 2.63) maintained the bond strength values (p ≥ 0.05), while G2T1 (10.62C ± 4.32) and G4T1 (4.49D ± 2.49) presented a decrease in this values. CONCLUSION: The hydrophobic two-step adhesive systems maintained the bond strength after 1-year water storage.