Humans have been using natural products for medicinal use for ages. Natural products of therapeutic importance are compounds derived from plants, animals, or any microorganism. Ginger is also one of the most commonly used condiments and a natural drug in vogue. It is a traditional medicine, having some active ingredients used for the treatment of numerous diseases. During recent research on ginger, various ingredients like zingerone, shogaol, and paradol have been obtained from it. Zingerone (4-(4-hydroxy-3-methoxyphenyl)-2-butanone) is a nontoxic and inexpensive compound with varied pharmacological activities. It is the least pungent component of Zingiber officinale. Zingerone is absent in fresh ginger but cooking or heating transforms gingerol to zingerone. Zingerone closely related to vanillin from vanilla and eugenol from clove. Zingerone has potent anti-inflammatory, antidiabetic, antilipolytic, antidiarrhoeic, antispasmodic, and so forth properties. Besides, it displays the property of enhancing growth and immune stimulation. It behaves as appetite stimulant, anxiolytic, antithrombotic, radiation protective, and antimicrobial. Also, it inhibits the reactive nitrogen species which are important in causing Alzheimer's disease and many other disorders. This review is written to shed light on the various pharmacological properties of zingerone and its role in alleviating numerous human and animal diseases.

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Paddy straw is a major agro-residue fed to ruminants in India. Feeding only rice straw does not provide enough nutrients to the ruminants even for maintenance due to the low nutritive value of this highly lignified material containing high concentration of anti-nutrition factors like lignin, silicates and oxalates. Despite the improvements of crop residues through various processing methods such as physical and chemical, the efficient utilization to desirable extent is still awaited. So utilization of paddy straw in association with concept of complete feed along with biological agents is need of the hour to maximize advantage from given feeds in animal production systems.

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Introduction: Prostate gland involved by a no. of benign and malignant diseases is a common cause of morbidity and mortality in the elderly men. The present study was an attempt to understand the histopathological spectrum of prostatic lesions in the specimens received by a tertiary care hospital.Material and Methods: 433 cases of prostatic specimens including TURP chips, TRUS guided biopsies and Prostatic specimens received in the Department of Pathology, Government Medical College Srinagar were included in the present study. There were 344 needle biopsies and 82 TURP chips. All the specimens were fixed in 10% neutral buffered formalin and thin sections were stained with Hematoxylin and Eosin stain (H&E stain). Relevant clinical data including age, the presenting complaints and S.PSA values in suspected cases of carcinoma prostate were recorded.Results: A total of 433 prostate specimens were received during the period of three years. The specimens included 344 TURP chips and 82 TRUS guided biopsies. 7 prostectomy specimens were also included. The age of the patients varied from 42 years to 89 years. There were 380 benign cases and 53 malignant cases. The most common presenting feature was increased frequency of micturition followed by difficulty in starting and stopping the stream of urine. Among benign lesions the most frequent histopathologi cal entity observed was benign nodular hyperplasia. The most common age of presentation was the sixth to seventh decade of life. Almost all neoplasms of the prostate were prostatic adenocarcinomas with most of the cases seen in the sixth to seventh decade of life with another peak in the seventh to eight decade of life. Conclusion:A variety of benign and malignant lesions are seen in prostatic specimens. These need to be differentiated and classified. Benign nodular hyperplasia is the most common benign lesion and prostatic adenocarcinoma is the most common malignant lesion of Prostate. Perineural invasion is a significant finding and guide. Serum PSA is a useful adjunct in cases where the values are higher.

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