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Objective: Cervical cancer is a common cancer in females. Clinicopathological features vary and are heterogeneous in different studies. This study was taken up to know the clinicopathological correlation in squamous cell carcinoma (SCC) of the cervix in our population. Methods: This is a cross-section study. Histologically confirmed cases of squamous cell carcinoma of the cervix are considered. Clinical history, socio-demographic details, clinical findings including stage and histological grade of the disease are noted and statistically analyzed. Result: The age range of cases was 30-80 years, with a mean of 54.2±12.0. The age range at marriage was 12-23 years, with a mean of 15.7±2.1. Parity ranged from 1 to 11, with a mean of 3.6±1.6. The p-value between bleeding pervagina and other symptoms versus no bleeding per-vagina and other symptoms, stage of disease between pre & peri-menopausal, and post-menopausal cases were 0.011 and 0.020, respectively. Growth followed by bleeding was common clinical findings. The p-value between the stage of the disease and age, histological grade and parity, histological grade and clinical features was 0.032, 0.001, and 0.031 respectively. Conclusion: Younger age group cases and pre & peri-menopausal women present the disease at an early stage. Older age women present at an advanced stage. Higher parity had a higher risk of cervical cancer of well differentiated SCC. Bleeding per-vagina was a more common clinical presentation in post-menopausal women. Clinical features of bleeding per vagina with other symptoms were more common in well differentiated SCC.

Sustained attention (SA) is a vital function mediated by the right frontal - parietal cortex. The digit vigilance test (DVT) measures SA. Assessment of SA in students for their academic excellence is considered to be an essential part of a neuropsychological evaluation. The objective of this study is to determine SA in students undergoing training of integrated Yoga module (IYM). A total of 66 university students aged between 18-37 years participated in this study with a single group pre-post design. The DVT data was collected before and after the IYM. Statistical Package for Social Sciences version 19 was used for data analysis. The Kolmogorov-Smirnov test showed that the data were not normally distributed. The Wilcoxon's signed ranks test was used to compare means of data. The data analysis showed 11.66% decrease (P < 0.001) in total time taken for DVT and 31.90% decrease (P < 0.001) in error scores for DVT. The present study suggests that IYM can result in improvement of SA among students, thus paving the way for their academic excellence. Additional well-designed studies are needed before a strong recommendation can be made.

Now a days recurrent UTI is on common infection among the people, more common in women, particularly in child bearing age. The current research aims at providing a cost effective, long standing treatment protocol for the management of recurrent UTI and also for minimizing the recurrence of symptoms for a longer duration.. The objective of the study is to assess the effect of naturopathic modalities in the signs, symptoms and microscopical features of recurrent urinary tract infection. The study was a before and after Quasi – experimental or Non- randomized design. Data from an individual case sheet Proforma specifying demographical data, general history, clinical history related to urinary tract infection, physical examinations, laboratory investigation, data related with treatment and its response were collected. A consultation and examination was performed to grade the signs and symptoms. Grading was done before and after treatment. Routine blood investigation including erythrocyte sedimentation rate (ESR) and data related to presence of pus cells in urine were also collected. The naturopathic modalities including hot hip bath, abdominal hot compress, juice therapy and diet control is found to be therapeutically very effective in reducing the symptoms of urinary tract infection. Juice therapy used in the study has diuretic and anti-inflammatory properties and provide good results.

Objective: Flavonoids from the crude seeds extract of Pongamia pinnata L., dried fruit powder of Morinda citrifolia L., bark of Mangifera indica L., and rhizome of Zingiber officinale Rosc. were screened for xanthine oxidase (XO) inhibition at different concentration. The inhibitory potential of quercetin and allopurinol were used for the determination of 50% inhibitory concentration (IC 50 ) and K i values.Methods: Isolation of flavonoids from the plant extracts was processed by column chromatography and tested for XO inhibitory activity in the range of 6-800 µg/ml. Results:The results demonstrated that optimized flavonoids extract of P. pinnata L. exhibited promising XO inhibition. P. pinnata L., M. indica L., and Z. officinale Rosc. had IC 50 in the concentration of 8.74 mM, 1.09 mM, 5.4 mM and Ki 0.35 mM, 1.73 mM, 2.7 mM, respectively. Conclusion:The study showed that plant species under investigation exhibited XO inhibition by optimized flavonoid extract. P. pinnata L. indicated promising XO inhibition compared to other plant extracts. Flavonoids can be used as a potent inhibitor of XO an alternative to allopurinol.

Background: The primary objective of the study is to manage the level of “sensitivity of salivary over serum glucose” in patients whohave been suffering from type 2 diabetes mellitus patients.Materials and Methods: There are two groups have been selected for this study for the purpose of gathering samples. In that case,Group A includes individuals below 60 years, and also their health condition was checked before the selection as a sample. In addition,Group B incorporates 60 adults after observing their diabetes levels. In that case, it can be observed that Group B has successfullycontrolled their type2 of diabetes. In order to determine the glycosylated hemoglobin and serum glucose present in the blood, the bloodsamples (“1.5ml of venous Blood”) were gathered with the help of EDTA. In this context, it is required to use a sterile container tocollect stimulated saliva from each of the groups. In this study, the “microcolumn method” has been used for the estimation of glucoseof the subjected groups. In the next phase, the result can be obtained with the help of statistical analysis with “ANOVA” and “correlationtest”.Results: In every group, the level of salivary glucose has been enhanced and also observed after doing a proper comparison. Thepresence of HbAlCc can enhance the percentage of glucose in a certain group. After doing the correlation Analysis, it can be foundthat a positive result (P<0.001) occurs between the two factors such as “salivary glucose level with HbAlc” and “serum glucose level”.Conclusion: The study has depicted that, salivary glucose can be used as a form of “noninvasive diagnostic aid”. The term diabetes hasbeen influenced by the function and composition of the salivary method.

Background: Ovarian torsion refers to the complete or partial rotation of the ovary. It is one of the most common gynecologic surgical emergencies affecting all ages. Early diagnosis can help prevent irreversible damage to ovary. Objective of this study was to analyze the clinical, and pathological characteristics of surgically proven cases of ovarian torsion at a tertiary care centre. Methods: This retrospective study was carried out from January 2016 to October 2019. Medical records of 20 cases of adnexal torsion were selected and analyzed retrospectively for age, parity, risk factors, clinical presentation, ultrasound and color Doppler features, management, pathological results and post-operative outcome.Results: A total of 20 patients with ovarian torsion were identified. Most commonly ovarian torsion was seen in reproductive age group (mean age of 31.4yrs) and in multiparous women (70%). More than 75% of the cases were associated with risk factors. Common presenting symptoms were sudden onset abdominal or pelvic pain (100%), vomiting (80%) and fever (40%). Ultrasonogram had various findings like mixed echogenic mass (35%), homogenously echogenic cyst (45%) anechoic cyst (20%) and free fluid (20%). Doppler studies showed absent arterial and venous flow in 25% of the cases. Cases were managed by detorsion & cystectomy (15%), unilateral salpingooophorectomy (70%), bilateral salpingooophorectomy (10%) and TAH with BSO (5%). Histopathology revealed benign serous epithelial tumors (40%), mucinous tumors (25%), mature teratoma (5%), corpus luteal cyst (10%), Para ovarian cyst (10%), gangrenous cyst (10%). Conclusions: Adnexal torsion is one of the gynecologic emergencies. Most of the findings in our study are reconfirmation of the pre-existing data based on a large number. However, we believe that area-specific information of this condition is mandatory for the medico-policy making in this institute. This data also reemphasizes the importance that the emergency physicians should have high index of concern/suspicion of ovarian tumor torsion when they encountered acute abdomen in women.

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