BackgroundChikungunya virus causes mosquito-transmitted infection that leads to extensive morbidity affecting substantial quality of life. Disease associated morbidity, quality of life, and financial loss are seldom reported in resources limited countries, such as Bangladesh. We reported the acute clinical profile, quality of life and consequent economic burden of the affected individuals in the recent chikungunya outbreak (May to September 2017) in Dhaka city, Bangladesh.MethodsWe conducted a cross-sectional study during the peak of chikungunya outbreak (July 24 to August 5, 2017) to document the clinical profiles of confirmed cases (laboratory test positive) and probable cases diagnosed by medical practitioners. Data related to clinical symptoms, treatment cost, loss of productivity due to missing work days, and quality of life during their first two-weeks of symptom onset were collected via face to face interview using a structured questionnaire. World Health Organization endorsed questionnaire was used to assess the quality of life.ResultsA total of 1,326 chikungunya cases were investigated. Multivariate analysis of major clinical variables showed no statistically significant differences between confirmed and probable cases. All the patients reported joint pain and fever. Other more frequently reported symptoms include headache, loss of appetite, rash, myalgia, and itching. Arthralgia was polyarticular in 56.3% of the patients. Notably, more than 70% patients reported joint pain as the first presenting symptom. About 83% of the patients reported low to very low overall quality of life. Nearly 30% of the patients lost more than 10 days of productivity due to severe arthropathy.ConclusionsThis study represents one of the largest samples studied so far around the world describing the clinical profile of chikungunya infection. Our findings would contribute to establish an effective syndromic surveillance system for early detection and timely public health intervention of future chikungunya outbreaks in resource-limited settings like Bangladesh.

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Blood agar is needed for culture of various organisms. As sheep blood is needed for it’s preparation, many small laboratories specially those of rural areas can not prepare it due to difficulty in collection of sheep blood. So, either they do not do the culture or do it without blood agar which cause missing of some important organisms. In this study Brain heart infusion agar was used together with Blood agar to assess it’s efficacy as an alternative of Blood agar. In total 1256 various samples were cultured, on Blood agar , Brain heart Infusion agar and MacConkey agar. Out of 1256 samples 404 samples showed growth of various organisms. It was noted that all bacteria including Enterococcus sp. grew equally in blood agar and BHIA. Brain heart infusion agar can be used as a surrogate of blood agar. Bangladesh J Med Microbiol 2018; 12 (1): 24-26

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A cross sectional study was carried out on patients with diabetic foot lesions to determine the spectrum of aerobic microbial flora and to determine the microbial pathogens of the diabetic foot lesions and their antimicrobial sensitivity pattern. A total of 226 organisms were isolated from 218 patients and polymicrobial infection was found in 3.7 % cases. Age of the study population ranged from 20 - >80 yrs of which most of the patients were from 40 to 70 yrs (81 %). Male female ratio was= 3:1. In this study, Pseudomonas sp. (22.1 %), Proteus mirabilis (16.4 %) and S. aureus (14.6 %) were the predominant organisms isolated. Antimicrobial susceptibility pattern of the isolates were done in which imipenem and ciprofloxacin were found to be the most effective against all organisms.DOI: http://dx.doi.org/10.3329/bjmm.v6i2.19372 Bangladesh J Med Microbiol 2012; 06(02): 20-23

Extended Spectrum ß-Lactamase (ESBL) acquired by bacteria is a highly effective weapon for drug resistance against a wide range of antibiotics (penicillins, cephalosporins and monobactams). ESBLs have continued to increase in variety and prevalence and are now a global health concern including Bangladesh. They are associated with failure in effective treatment, increased morbidity and mortality, poor outcomes, increases in length of stay(LOS) in hospital and health care costs. So, it is important to identify it and take necessary measures to treat with appropriate antimicrobial therapy. This study has been designed to establish an easy method for routine reporting of ESBL organisms and notify it's incidence in Health Care settings.

Bacterial vaginosis is the commonest cause of abnormal vaginal discharge in women of reproductive age. A total 200 women aged 15- 45 years with history of abnormal vaginal discharge were included as study population. Fifty women without such history of discharge were taken as healthy control. Two vaginal swab samples were taken from each case and control. These swab samples were subjected to test by Gram stain (Nugent method) and culture. 21.5 % of the cases were diagnosed as bacterial vaginosis by Gram stain (Nugent method) and 21 % by culture. Clindamycin was susceptible to G. vaginalis in (90.5%) followed by metronidazol (76.1 %), chloramphenicol (71.4 %) and erythromycin (66.7 %). Out of 50 cases of recurrent bacterial vaginosis, G. vaginalis was isolated from 15 (30 %) cases, of which 5 (33.3 %) were sensitive and 10 (66.7 %) were resistant to metronidazol, while all 15 cases were sensitive to clindamycin.DOI: http://dx.doi.org/10.3329/bjmm.v5i1.15814 Bangladesh J Med Microbiol 2011; 05 (01): 8-11