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Objective We aimed to investigate uric acid and albumin ratio (UA/A) as a marker of short-term mortality in acute kidney injury (AKI). Both uric acid and albumin are strongly correlated with the development and mortality of AKI. MethodsThe patients hospitalized from May 2019 to September 2019 for AKI were included in this study. The diagnostic odds ratio (DOR), Youden index (J), and the area under a receiver operating characteristic curve (AUROC) determined a cut-off UA/A ratio for mortality. Cox-regression analysis was performed to identify UA/A as a prognostic marker of the 30-day mortality rate.Results A total of 171 patients with an average age of 69.20 ± 13.0 (45.6% women) were included in the study. The average UA/A ratio was 3.3 ± 1.5 mg/g and 2.5 ± 1.0 mg/g in the nonsurvivor and survivor groups, respectively (P = 0.001). The best cut-off UA/A ratio associated with mortality was determined as 2.4 mg/g with a specificity of 52% and a sensitivity of 77% (DOR, 3.6; J, 28.8; AUROC, 0.644). Thirty-day cumulative survival rates of the low and high UA/A ratio groups were 85.9 ± 4.0% and 63.7 ± 5.0%, respectively. The estimated survival times of the low and high UA/A ratio groups were 27.7 days (95% confidence interval [CI], 26.2-29.3) and 23.9 days (95% Cl, 22.0-25.9), respectively. ConclusionWe found a direct correlation between 30-day mortality and UA/A ratio at initial presentation in AKI patients regardless of age, comorbidities, and clinical and laboratory findings, including albuminuria.

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Background This study aims to determine the stroke prevalence in Akçakoca which is a rural area in Turkey. Methods The study was designed as a cross-sectional, door-to-door survey. The stroke questionnaire was completed by a trained team in the presence of the participants according to their answers. Based on the screenings, patients who had been diagnosed with stroke previously were reexamined by a neurologist and determined the prevalence values, risk factors, and stroke types. Results A total of 3750 people over 44 years old were reached in the screenings. It was determined that 83 people had previously suffered a stroke. The prevalence rate of stroke in those above 44 years was found to be 2.2 (98% confidence level and ± 2% margin of error). 70 (84.3%) patients had suffered an ischemic stroke while 12 (14.5%) had suffered a hemorrhagic stroke. Male/female ratio was 1.1. Conclusion The results of this study give the prevalence rate of stroke among the Turkish population living in a rural area. Due to a lack of other similar studies, it is impossible to make any data comparison. However, the results of this study help shed light on the stroke prevalence rate.

Background: The neutrophil-to-lymphocyte ratio (NLR) is a simple and inexpensive examination that is considered to show inflammation. In this study, which included a control group, the authors aimed to investigate if there was a relationship between glycaemic regulation parameters and NLR in patients with Type 2 diabetes mellitus. Material and Methods: A total of 278 Type 2 diabetic patients were included in the study. An additional total of 148 healthy people were also included as a control group. NLR was calculated by dividing the absolute neutrophil number by the absolute lymphocyte number. The patients were divided into two groups: the good glycaemic control group (HbA1c ≤7.5%) and the poor glycaemic control group (HbA1c >7.5%). NLR was compared between the diabetic groups. In addition, NLR was compared with diabetic patients and control group. Results: The NLR was statistically and significantly higher in the poor glycaemic control group compared to the good glycaemic control group (2.48 [1.97–2.60] to 2.07 [1.72–2.40], respectively; p=0.020). In addition, NLR was significantly higher in the patients than in the control group (2.30 [2.04–2.49] to 2.01 [1.85–2.18], respectively; p=0.002). Conclusion: According to the authors’ knowledge, increased NLR may be associated with poor glycaemic control in Type 2 diabetic patients. NLR may be useful used as an easily measurable, noninvasive, available, and cost-effective parameter for the follow-up of diabetic patients.

ÖzetAmaç: Bu çalışmada hastanemiz dahiliye polikliniğine baş-vuran tip 2 diyabetli hastalarında glisemik hedeflere ulaşma oranları ve glisemik hedefe ulaşanların ilaç kullanım profilleri incelenmiştir. Gereç ve Yöntem:Mart 2011-Mayıs 2011 arasında üç ay boyunca hastanemiz İç Hastalıkları Polikliniği'ne başvuran 375 tip 2 diyabet tanılı hastanın HbA1c değerlerine bakıldı, hastalık yaşı ve ilaç kullanımı sorgulandı. HbA1c ≤%7 olan hastaların (iyi kontrol grubu) ilaç profilleri incelendi. Bulgular:Üç yüz yetmiş beş hastanın hastalık yaşı dikkate alınmadan değerlendirildiğinde %66'sı (n=248) iyi kontrol grubunda idi. Glisemik hedefe ulaşmış bu hastaların %81'i oral antidiyabetik (OAD) (n=203), %15'i OAD + insülin (n=36), %4'ü sadece insülin (n=9) kullanmaktaydı. Hastalık yaşı beş yıl ve üzeri olan hastaları incelendiğimizde (n=169) ise 169 hastanın %36'sı iyi kontrol grubunda idi (n=61). Glisemik hedefe ulaşmış bu hastaların %98'i OAD (n=60), %2'si OAD + insülin (n=1) kullanmaktaydı.Sonuç: Diyabetik popülasyonda hastalık yaşı ilerledikçe iyi kontrol grubu oranı azalmaktadır. İyi kontrol grubunda hastalık yaşı ilerledikçe insülin kullanımının artması beklenirken çalışmamızda oral antidiyabetik kullanan hastaların daha fazla olduğunu tespit ettik.

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