This study has shown that an increased MPV is closely associated with poor glycaemic control, which may be a risk factor for diabetic retinopathy. Nonetheless, further prospective studies are needed to assess the relationship between MPV, glycaemic indices and microvascular complications.

In conclusion, NLR, a parameter easily found in routine blood counts of CKD patients, is a marker with prognostic value for the presence and degree of proteinuria.

Background and aim: Omentin-1 is suggested to affect inversely atherosclerosis (AS). Data about omentin-1 is limited to chronic kidney disease (CKD). Our aim was to examine omentin-1 in non-diabetic CKD patients who are not dialyzed and investigate its relationships with inflammation and carotid AS. Materials and Methods: We performed a cross-sectional study in 55 non-diabetic CKD patients and 30 healthy controls. Baseline clinical and laboratory data were obtained for all participants. Serum omentin-1 and interleukin-6 (IL-6) levels were measured according to the manufacturer's instructions. Carotic plaque and intima-media thickness (IMT) were assessed by carotid ultrasonography. The homeostasis model assessment of insulin resistance index (HOMA-IR) was used to assess IR. Results: Omentin-1 and IL-6 levels in the patient group were found to be higher than the control group; the differences were statistically significant (p ¼ 0.01 and p ¼ 0.04, respectively). Carotid IMT(mean) was significantly higher in the patient group (p ¼ 0.01). Omentin-1 did not correlate with IL-6 and IMT in the patient group (p ¼ 0.51 and p ¼ 0.76, respectively). In subgroup analysis, omentin-1 levels in patients with carotid plaque were lower than those without carotid plaque (179.5 AE 88.1 ng/ml and 185.9 AE 67.8 ng/ml, respectively). However, the difference was not statistically significant (p ¼ 0.47). Conclusion: We conclude that omentin-1 is higher in not dialyzed non-diabetic CKD and there is no correlation between omentin-1 and IL-6 or carotid IMT(mean).

After adjusting for age and BMI in a comparison of BMD between postmenopausal women with and without metabolic syndrome, it was revealed that metabolic syndrome has no positive or negative effect on BMD. In contrast, a negative correlation was identified between FBG and HbA1c levels and lumbar BMD, suggesting that poor glycemic control may have a negative effect on lumbar BMD in this group of patients.

Sjögren's syndrome is mainly affects the exocrine glands. Patients usually complain of persistent dryness of the mouth and eyes. However, nonexocrine organs such as the kidneys are often affected in these patients. Distal renal tubular acidosis (dRTA) and interstitiel nephritis are common in Sjögren's syndrome. Nonetheless, severe hypokalemia and paralysis secondary to dRTA are unusual initial manifestation of Sjögren's syndrome. Here, we describe a case of a 48 year old women admitted to the emergency setting with severe hypokalemic paralysis and diagnosed Sjögren's syndrome.

Bu çalışmanın amacı hemodiyaliz hastalarında sinakalset kullanımının serum kalsiyum, fosfor ve paratiroid hormon üzerindeki etkisini incelemektir. Yöntem: Çalışma, 15 (9 E, 6 K) hemodiyaliz hastasında yapıldı. 3 ay süre ile sinakalset kullanan hastaların retrospektif olarak dosyaları incelendi. Biyokimya tetkikleri ve kan basıncı kayıtları kaydedildi. İstatistiksel analizler SPSS v 15 ile gerçekleştirildi. Bulgular: Serum kalsiyum, kalsiyum x fosfor ürünü ve paratiroid hormon düzeylerinde istatistiksel olarak anlamlı azalmalar saptandı (sırasıyla P=0.001, P=0.04 ve P=0.009). Fosfor düzeyi azalmakla birlikte farklılık istatistiksel olarak anlamlı bulunmadı. Üç hastada bulantı, üç hastada ise bulantı ve kusma gözlendi. Ayrıca üç hastada kalsiyum seviyesi 8 mg/dl'nin altına düştü. Sonuç: Sinakalset hemodiyaliz hastalarında serum kalsiyum, kalsiyum x fosfor ürünü ve paratiroid hormon düzeylerini anlamlı olarak azaltmaktadır. Tedavi sırasında bulantı, kusma ve hipokalsemi sık görülmektedir. Ancak, daha fazla hasta üzerinde yapılacak çalışmalara ihtiyaç vardır. Background:The purpose of this study is to examine the effect of cinacalcet on serum calcium, phosphorus, and parathyroid hormone in hemodialysis patients. Method: This study was performed in 15 hemodialysis patients. The medical records of patients taking cinacalcet for three months were examined. Biochemical tests and blood pressure were recorded. The statistical analysis was performed using SPSS v 15.0. P< 0.05 was considered statistically significant. Results: There were statistically significant decreases in calcium, calcium x phosphorus product and parathyroid hormone levels (P=0.001, P=0.04 and P=0.009 respectively). Phosphorus level was reduced but not significantly. Nausea was observed in three patients, nausea and vomiting in three patients, as well as hypocalcaemia. Conclusion: Cinacalcet significantly reduced serum calcium, calcium x phosphorus product, and parathyroid hormone levels in hemodialysis patients. Nausea, vomiting, and hypocalcaemia often develop during the therapy. However, further studies are needed in larger patients.

Mad honey poisoning syndrome is common in Turkey mostly in Black Sea Region. Gastrointestinal, cardiovascular and neurologic systems are mostly involved in this syndrome. Hypotension, bradycardia and visual disorders are usually encountered problems. Intravenous fluid and atropin therapy are successfully used in symptomatic patients. We report a 46 year old male with mad honey poisoning who presented with prolonged hypotension and bradycardia.