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Benzylidene acetals of 1,2- and 1,3-glycols are easily cleft by diisobutylaluminum hydride in a toluene solution at 0 °C–room temperature to give the corresponding monobenzyl ethers of the glycols. In general the reaction proceeds excellently in regioselective manner depending on the stereochemical environment.

A convenient one-flask synthesis of α-methylenealdehydes from primary alcohols has been established.

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A concise enantioselective route t o (-)-kainic acid (1) from (S)-2-(benzyloxymethyl)oxirane (2) has been established by ena n tio-and diastereo-selective i nt ramolecu la r 1,3-d i pola r cycl ization.