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Cellular senescence and aging result in a reduced ability to manage persistent types of inflammation. Thus, the chronic low-level inflammation associated with aging phenotype is called “inflammaging”. Inflammaging is not only related with age-associated chronic systemic diseases such as cardiovascular disease and diabetes, but also skin aging. As the largest organ of the body, skin is continuously exposed to external stressors such as UV radiation, air particulate matter, and human microbiome. In this review article, we present mechanisms for accumulation of senescence cells in different compartments of the skin based on cell types, and their association with skin resident immune cells to describe changes in cutaneous immunity during the aging process.

Various glass-ceramics were prepared based on the BaO-Al 2 O 3 -B 2 O 3 -SiO 2 system with the addition of La 2 O 3 , ZrO 2 , or NiO in an attempt to develop a suitable sealant for planar solid-oxide fuel cells operating at 800°C. To estimate the applicability of these glasses as suitable sealants, their thermal and chemical stabilities as well as the crystallization behavior and bonding characteristics of their parent glasses were investigated. The thermal properties and crystallization behavior of the parent glasses were dependent on the type of additive used, and the bonding characteristics were strongly influenced by the B 2 O 3 /SiO 2 value in the glass composition. Observation of microstructural change and chemical reaction at the glassceramic/electrolyte interface confirmed that the prepared glass-ceramics possessed long-term stability during heat treatment at the operation temperature for up to 1000 h. Journal of the American Ceramic No. 2 Fig. 6. Changes in CTE values of the various glass-ceramics with long-term heat treatment at 800°C (CTE values were measured from RT to 800°C in air with a heating rate of 5°C/min).

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