Background:Obesity is associated with a decrease in iron status, possibly it is an increase in hepcidin, an inflammatory protein that reduces iron absorption. Hepcidin is associated with iron homeostasis and inflammation. This study aims to determine differences in levels of hepcidin and ferritin of obesity pregnant women and normal weight before pregnancy. Subjects and Method: This was an analytic observational study with a case control design. A total of 62 pregnant women was selected by consecutive technique sampling and divided into 2 groups, namely obesity and normal weight before pregnancy. The study was conducted at RSIA Badrul Aini Medan and at RSUP H.Adam Malik Medan from September to December 2016. The dependent variable of this study was the weight before pregnancy. The independent variable washepcidin levels examined by ELISA method, ferritin content with Immunochemiluminescent method. The data analysis employed Mann Whitney's different test. Results: Median of hepcidin level in obese pregnant women before pregnancy was higher than pregnant mother with normal weight of 7.08 ng / mL (2.14 to 78.18). There was no difference in hepcidin level in both groups (p = 0.578). Median ferritin levels in obese pregnant women were higher than the normal weight of 20.57 μg / L (3.66 to 102.25). There was no difference of ferritin levels in both groups (p = 0.598). Conclusion:This study showed no difference in hepcidin levels and ferritin levels in obese pregnant women and normal weight before pregnancy.
Background: HIV transmission can be reduced by practicing appropriate prevention. Every centers have their own standardized regimens for antiretroviral therapy. The study aimed to determine HIV transmission after practicing standardized triple antiretroviral therapy adapted in Haji Adam Malik Hospital.Study Design: This is an cohort-analytic study conducted in Haji Adam Malik hospital. Medical records of HIVpositive mothers who did the antenatal care and delivered at Haji Adam Malik Hospital in 2009-2014 were collected. The standardized antiretroviral therapy adapted in Haji Adam Malik Hospital were applied. Follow up was done to all of the born children in order to determine HIV tranmission rate. Diagnosis of HIV in children under the age of 18 monthswere done by PCR (Polymerase Chain Reaction). If the child has been aged ≥18 months, the method of diagnosis is Rapid Test.Results: Of the 60 infants examined, 11 infantsaged <18 months enrolled in PCR tests, while 49 otherschildren were tested using rapid test. However, no virus were detected in all infants. Conclusion:The triple antiretroviral effectively prevent the HIV transmission from mother to children.
Kanker payudara merupakan penyakit kanker tertinggi di Indonesia. Berdasarkan data Kementrian Kesehatan RI tahun 2013 sebesar 0,5% atau 61.682 penderita. Kejadian kanker payudara dapat terjadi dikarenakan beberapa faktor risiko. Berdasarkan catatan rekam medis jumlah penderita kanker payudara pada tahun 2016 di RSUD Dr. Pirngadi Medan dari bulan januari sampai april sebanyak 284 orang. Jenis penelitian survei analitik dengan pendekatan case control. Penelitian ini dilakukan pada bulan Oktober sampai Desemberi 2016. Jumlah responden dalam penelitian ini adalah sebanyak 136 orang, dimana 68 responden pada kelopok kasus dan 68 responden pada kelompok kontrol. Analisis data multivariat enggunakan uji logistic regression. Hasil penelitian diperoleh bahwa variabel riwayat keluarga menderita kanker merupakan faktor risiko yang paling dominan berpengaruh terhadap kejadian kanker payudara di RSUD Dr. Pirngadi Medan. Hal ini diperoleh dari nilai Exp.(B) yakni 10,726 yang artinya dengan adanya faktor riwayat keluarga menderita kanker pada wanita, menyebabkan 10,761 kali lebih berisiko untuk menderita kanker payudara dibanding dengan faktor risiko yang lain. Kepada petugas kesehatan yang bertugas di RSUD Dr. Pirngadi Kota Medan agar berupaya meningkatkan pengetahuan penderita maupun bukan penderita kanker payudara melalui promosi kesehatan yaitu penyuluhan tentang kanker payudara dan pencegahan dini kanker payudara serta teknik menyusui yang benar sehingga menurunkan angka kejadian kanker payudara.
Pregnancy is the growth and development of the intrauterine fetus starting from conception and ending until the onset of labor. Nausea and vomiting (emesis gravidarum) is a problem that is often experienced by pregnant women in early pregnancy. To determine the effect of giving ginger decoction and lemon inhalation therapy to the incidence of emesis gravidarum in first trimester pregnant women in the working area of the Marancar Health Center, Kaupaten Tapanuli Seatan in 2021. Methods: The research design used a quasi-experimental approach with a two group pre and post test design approach. The population and sample in the study were 30 people. The data were processed by univariate and bivariate analysis using paired sample t-test and independent t-test. Results : There is an effect of giving ginger stew on reducing the incidence ofadianemesis gravidarumandthere isthe effect of giving lemon inhalation aromatherapy to decreaseadianemesis gravidarum. Giving ginger decoction is more effective than giving lemon inhalation in dealing with the decrease in the incidence of nausea and vomiting in first trimester pregnant women in the Marancar Health Center Work Area in 2021. It is hoped that the results of this study can improve services in the health sector, especially in providing information about the effect of giving boiled ginger and aromatherapy lemon inhalation against canceradianemesis gravidarumin first trimester pregnant women.
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