In this paper, the authors analyze the dynamic behavior of a rigid polygonal part struck on a horizontal surface under the action of friction and present how to propel the part to a desired configuration through the impulsive operation. In the dynamic analysis of the impulsive operation, the part motion is typically analyzed in two phases, impact motion and sliding motion. These are usually analyzed in reverse order of occurrence. The authors characterize the impact and sliding dynamics with friction for polygonal parts and develop an approach to compute the inverse dynamic solution for motion planning of the impulsive operation. Finally, the authors verify the effectiveness of the simulation results and the developed motion plans through comparison with experimental results using a high-speed video camera.
PurposeTo evaluate the efficacy of anti-vascular endothelial growth factor (VEGF) compared with observation for treating acute central serous chorioretinopathy (CSC).MethodsA retrospective study of 36 patients with acute CSC, including 21 patients treated with anti-VEGF (anti-VEGF group) and 15 patients with observation (observation group). Patients in the anti-VEGF group received a single dose of bevacizumab or ranibizumab at baseline. Best-corrected visual acuity (BCVA), central foveal thickness (CFT) and resolution of subretinal fluid (SRF) on optical coherence tomography (OCT) were assessed. The integrity of the foveal inner segment/outer segment (IS/OS) line at 12 months was also analyzed.ResultsResolution of SRF was achieved in 20 of 21 eyes in the anti-VEGF group and in 12 of 15 eyes in the observation group (p = 0.151). Mean BCVA and CFT were not different between the two groups at 12 months (p > 0.05). The amount of change in BCVA, however, differed significantly between the groups (p = 0.044). Final OCT more frequently detected the foveal IS/OS line in the anti-VEGF group than in the observation group (p = 0.012).ConclusionsIn terms of BCVA, anti-VEGF and observation only had similar therapeutic effects in acute CSC patients. In some patients, however, the rapid resolution of SRF by anti-VEGF might reduce the risk of photoreceptor degeneration and improve long-term visual acuity.
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