Introduction: Various studies have demonstrated superiority of SAAG (serum ascites albumin gradient) in classifying ascites compared to transudate-exudate concept but with conflicting observations. Ascitic fluid total protein (AFTP) level in ascitic fluid is a much cheaper alternative to the serum ascites albumin gradient ratio. Hence in the study, we have compared the diagnostic accuracy of the old cheaper traditional method against the new method. Methods: Total 102 patients of Ascites were included in the study from J.A. group of hospital, G.R.Medical College (M.P.) in year 2013-15. All medical causes of ascites were included in our study and Non medical causes were excluded. The collected data was analyzed by using Pearson Chi-square statistical analysis to determine correlation between variables. Result: For prediction of liver disease it was found that SAAG was significantly (p value 0.0341) more predictive of Liver disease compared to AFTP. SAAG (p value<0.0009) and AFTP (p value 0.49) were both significant for differentiating cause of ascites when comparison was done between liver and non-liver disease. Conclusion: AFTP is a good surrogate marker for detection of liver disease in ascites. AFTP is an excellent diagnostic test for detection of certain extra hepatic diseases leading to ascites like tubercular peritonitis sub-acute bacterial peritonitis and anaemia-hypo-proteinemia.
OBJECTIVE:Increased uric acid level in case of Type II Diabetes Mellitus patient is associated with increased risk of Coronary Artery Disease (CAD) compared to those Type II Diabetes Mellitus who have normal uric acid level. METHOD: Total 100 patients of Type II Diabetes Mellitus (known case of Type II Diabetes Mellitus under treatment and also newly diagnosed cases.) were selected. 50 patients admitted or attending OPD selected as controls who were non-diabetic, diagnosed by screening with Fasting Blood Sugar, Random Blood Sugar and without any symptoms of Hyperglycaemia. RESULTS: In overall diabetics with CAD, serum uric acid level is >7.0mg/dL in 14/49 patients compared to without CAD having serum uric acid levels <7.0mg/dl in all 51 patients. The results were significant with p <0.001. Mean Serum Uric Acid Levels of all cases of Type II Diabetes Mellitus was higher than controls, with value of 5.14+1.25mg/dl, which was statistically significant with p<0.0001. CONCLUSION: Serum Uric Acid level in both group that is in those who were known case of Type II Diabetes Mellitus and also newly diagnosed cases of Type II Diabetes Mellitus is higher than control group. Also increased serum uric acid level is also responsible for the complication of Type II Diabetes Mellitus like Coronary Artery Disease.
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