Hyperuricaemia as a Predictor of Complication in Type Ii Diabetes Mellitus

Abstract

OBJECTIVE:Increased uric acid level in case of Type II Diabetes Mellitus patient is associated with increased risk of Coronary Artery Disease (CAD) compared to those Type II Diabetes Mellitus who have normal uric acid level. METHOD: Total 100 patients of Type II Diabetes Mellitus (known case of Type II Diabetes Mellitus under treatment and also newly diagnosed cases.) were selected. 50 patients admitted or attending OPD selected as controls who were non-diabetic, diagnosed by screening with Fasting Blood Sugar, Random Blood Sugar and without any symptoms of Hyperglycaemia. RESULTS: In overall diabetics with CAD, serum uric acid level is >7.0mg/dL in 14/49 patients compared to without CAD having serum uric acid levels <7.0mg/dl in all 51 patients. The results were significant with p <0.001. Mean Serum Uric Acid Levels of all cases of Type II Diabetes Mellitus was higher than controls, with value of 5.14+1.25mg/dl, which was statistically significant with p<0.0001. CONCLUSION: Serum Uric Acid level in both group that is in those who were known case of Type II Diabetes Mellitus and also newly diagnosed cases of Type II Diabetes Mellitus is higher than control group. Also increased serum uric acid level is also responsible for the complication of Type II Diabetes Mellitus like Coronary Artery Disease.