In a defined population, the estimated overall age- and sex-adjusted annual incidence of pseudoexfoliation syndrome was 25.9 per 100,000 population, while the estimated overall age- and sex-adjusted annual incidence of pseudoexfoliation glaucoma was 9.9 per 100,000 population. The incidence of both diseases was higher in females and increased with advancing age.

Lesion location and drug use that affects virus activity may influence the severity of lesion border opacity, a measure that may be more useful than lesion type in future clinical studies of CMV retinitis. In contrast to earlier concepts, CMV retinitis does not seem to be a fovea-sparing disease. Findings in this study can serve as a reference for investigations into possible changes in CMV retinitis since the introduction of HAART.

In a geographically defined population of PEX patients, 16% required treatment upon presentation. Of the remaining PEX patients, 44% received therapy over the next 15 years.

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