An increase in the incidence of diabetes mellitus type 2 (DM-2) has been observed from 1.1% in 2007 to 1.5% in 2018 with incidents occur in both urban areas and rural areas of Indonesia. Garut as one of the rural areas in Indonesia is the fourth district with the highest DM-2 incidence in West Java Province, Idnonesia. Physical activity is considered to affect the glycemic control and weight loss in DM-2 patients. Therefore, the purpose of this study was to determine the relation between the physical activity level and blood glucose level in DM-2 patients in Garut, Indonesia. This was a cross-sectional observational analytic study on 46 DM-2 patients who were the members of the Garut Branch of the Indonesian Diabetes Association (PERSADIA), in May 2018. The physical activity level was measured using the International Physical Activity Questionnaire (IPAQ) while the blood glucose level was measured using fasting blood glucose level test. Data were then analyzed using analysis of variance test. Results showed that most participants had a low level of physical activity (52.2%) while the lowest fasting blood glucose was obtained from patients with high physical activity (98.63±11.6), compared to those with moderate and low physical activity levels (123.43±20.16 and 164.21±19.04 mg/dL, respectively) with p=0.000 (p<0.05). Lifestyle changes, especially in the form of the lack physical activity, were seen alsonin the rural area in Indonesia. High physical activity level is the most effective measure to lower fasting blood glucose level in DM-2 patients. AbstrakKejadian pasien diabetes mellitus tipe 2 (DM-2) pada tahun 2018 (1,5%) mengalami peningkatan dibanding dengan tahun 2007 (1,1%), terjadi baik di daerah perkotaan dan pedesaan di Indonesia. Garut sebagai salah satu daerah pedesaan di Indonesia adalah salah satu kabupaten dengan insidens DM-2 terbesar keempat di Jawa Barat-Indonesia. Aktivitas fisik dianggap memengaruhi kontrol glikemik dan penurunan berat badan pada pasien DM-2. Oleh karena itu, tujuan dari penelitian ini adalah mengetahui hubungan tingkat aktivitas fisik dengan kadar glukosa darah pada pasien DM-2 di Garut-Indonesia. Subjek penelitian ini adalah 46 pasien DM-2 yang tergabung dalam Persatuan Diabetes Indonesia (PERSADIA), cabang Kabupaten Garut, pada Mei 2018. Metode penelitian yang digunakan adalah analitik observasional dengan metode cross-sectional. International Physical Activity Questionnaire (IPAQ) sebagai alat untuk mengukur tingkat aktivitas fisik, selain itu dilakukan pengukuran kadar glukosa darah puasa. Data dianalisis menggunakan analysis of variance test. Hasil penelitian menunjukkan bahwa sebagian besar peserta memiliki tingkat aktivitas fisik yang rendah (52,2%) dan glukosa darah puasa terendah diperoleh dari pasien dengan aktivitas fisik yang tinggi (98,63±11,6) dibanding dengan aktivitas fisik sedang dan rendah (123,43±20,16 dan 164,21±19,04 mg/dL), dengan p=0.000 (p<0,05). Perubahan gaya hidup terutama kurangnya aktivitas fisik juga terjadi di daerah pedesaan di Indonesia dan akti...
Infeksi saluran napas menduduki peringkat pertama dalam kelompok penyakit penyebab rawat jalan. Salah satu penyebabnya tingkat polusi udara. World Health Organization (WHO) menyatakan polusi udara bertanggung jawab atas 200 ribu kematian di daerah perkotaan dan 87% kasus kematian yang terjadi di negara berkembang pada tahun 2012. Peningkatan jumlah kendaraan bermotor merupakan penyebab polusi udara di dunia maupun Indonesia. Badan Statistik (BPS) menyatakan kendaraan bermotor di Indonesia akan terus meningkat dan tercatat pada tahun 2016 terdapat 129.281.079 kendaraan. Populasi yang sangat rentan terhadap penurunan fungsi organ paru adalah pekerja outdoor, salah satunya adalah supir angkot akibat terpapar langsung oleh polusi udara dan tidak menggunakan masker sebagai alat pelindung diri. Tujuan penelitian ini mengetahui pengaruh lama kerja terhadap fungsi paru pada supir angkot jurusan Cimahi di Terminal Leuwi Panjang Bandung periode Maret–Mei tahun 2018. Pengukuran fungsi paru menggunakan spirometer. Penelitian ini menggunakan desain analitik observasional dengan rancangan cross sectional terhadap 40 responden. Analisis statistika menggunakan Pearson correlation test. Hasil penelitian ini 16 responden (40%) memiliki lama kerja £5 tahun dan 24 responden (60%) lama kerja >5-15 tahun, memiliki rerata usia 31,27 tahun, berat badan 61,8 kg, tinggi badan 168,35 cm, dan IMT 21,79 kg/m2. Terdapat 17 responden (42%) memiliki fungsi paru normal, 23 responden (58%) mengalami gangguan restriktif fungsi paru dan sebagian besar responden dengan fungsi paru restriktif memiliki lama kerja >5-15 tahun p=0,00. Simpulan terdapat pengaruh lama kerja terhadap fungsi paru supir angkot jurusan Cimahi. THE EFFECT OF LENGTH OF WORKING ON LUNG FUNCTION AT DRIVER OF CIMAHI DESTINATION AT TERMINAL LEUWI PANJANG BANDUNGRespiratory infections ranked first in the outpatient disease category. One of the main factors is high level of air pollution. World Health Organization (WHO) states that air pollution is responsible for 200,000 thousands of deaths in urban area and 87% of the total deaths in developing countries in 2012. The increase in the number of vehicles is the cause of air pollution in the world including in Indonesia. Statistical agency claimed that the number of vehicles in Indonesia would grow exponentially and it has been recorded that there was 129,281,079 vehicles in 2016. Populations which are highly susceptible to decline in lung function is field workers, one of them is drivers of public transportation due to direct exposure of air pollution and this is exacerbated by the disuse of mask as self-protection. The aim of this research was to discover the relationship between the long working hours and lung function on the drivers of public transportation to Cimahi as the destination at Terminal Lauwi Panjang Bandung period on March–May in 2018. Lung function measurement using spirometer. The research design was analytic observasional using cross sectional design by 40 respondents and statistics analysis with Pearson Correlation test. The results of this study indicated 16 respondents (40%) with length working £5 years dan 24 respondents (60%) with length working >5-15 years had mean of age 31.27 years, body weight 61.8 kg, height 168.35 cm, and IMT 21.79 kg/m2. 17 respondents (42%) had normal function of lung and 23 respondents (58%) decrease the function of lung and most of the respondents who experienced restrictive had length working >5-15 years (p=0.00). In conclusion, there is effect of length of working on lung function at driver of Cimahi destination.
Until now, the world is still facing the COVID-19 pandemic caused by SARS-CoV-2. The number of deaths of COVID-19 patients in Indonesia is quite large when compared to other countries. Clinical manifestations, comorbidities, length of stay, and the mortality of COVID-19 vary widely in each study. This study analyzes clinical characteristics, comorbidities, length of stay, and mortality of COVID-19 patients in RSUD Cideres, Majalengka, West Java. This study is an observational study with total sampling and purposive sampling. Subjects were patients with nasal swabs confirmed SARS-CoV-2 and hospitalized at RSUD Cideres from January to July 2021. Clinical manifestations, comorbidities, length of stay, and mortality of COVID-19 patients aged ≥17 years old, were extracted from medical records. Results showed that the majority of 213 COVID-19 patients were age 41–60 years 114 (53.5%), female 114 (53.5%), with an upper respiratory tract in 207 (97.1%), and shortness of breath in 203 (95.3%) patients. 153 (71.8%) patients had a fever, while headache, diarrhea, and anosmia respectively 49 (23.0%), 19 (8.9%), and 10 (4.6%), respectively. Vital signs were the Glasgow Coma Scale (GCS) normal in 190 (89.2%) patients. Most of patients had respiration rate >20/min in 201 (94.3%), oxygen saturation <90% in 98 (46.0%), and chest x-rays: bronchopneumonia 134 (62.9%) and pneumonia 23 (10.7%). Comorbidities were hypertension, diabetes mellitus, and chronic heart failure in 74 (34.7%), 56 (26.2%), and 46 (11.7%) patients, respectively. The length of stay who died for 1–7 days (22 patients) and 8–14 days (9 patients); means almost all patients (29 of 32) died during the length of stay for 1–14 days. In conclusion, the majority of COVID-19 patients at RSUD Cideres are female, aged 41–60 years, had upper respiratory tract/shortness of breath, GCS normal, saturation oxygen <90%, chest x-rays: bronchopneumonia and pneumonia, comorbidities: hypertension, and length of stay for patients who died 1–7 days. KARAKTERISTIK KLINIS, KOMORBITAS, LAMA RAWAT, DAN MORTALITAS PASIEN COVID-19 DI RSUD CIDERES, MAJALENGKA, JAWA BARATHingga saat ini, dunia masih menghadapi pandemi COVID-19 yang disebabkan oleh SARS-CoV-2. Jumlah kematian pasien COVID-19 di Indonesia cukup besar jika dibanding dengan negara lain. Manifestasi klinis, komorbid, lama rawat, dan mortalitas pasien COVID-19 sangat bervariasi pada setiap penelitian. Tujuan penelitian ini menganalisis karakteristik klinis, komorbiditas, lama rawat, dan mortalitas pasien COVID-19 di RSUD Cideres, Majalengka, Jawa Barat. Penelitian ini adalah penelitian observasional dengan total sampling dan purposive sampling. Subjek adalah pasien dengan nasal swab terkonfirmasi SARS-CoV-2 dan dirawat di RSUD Cideres periode Januari hingga Juli 2021. Data manifestasi klinis, komorbid, lama rawat, dan mortalitas pasien COVID-19 usia ≥17 diambil dari rekam medik. Hasil menunjukkan bahwa mayoritas 213 pasien COVID-19 berusia 41–60 tahun 114 (53,5%) dan wanita 114 (53,5%) dengan keluhan saluran napas atas 207 (97,1%) dan napas pendek 203 (95,3%) pasien. 153 (71,8%) pasien mengalami demam, sedangkan sakit kepala, diare, dan anosmia masing-masing 49 (23,0%), 19 (8,9%), dan 10 (4,6%) pasien. Tanda vital Glasgow Coma Scale (GCS) normal pada 190 (89,2%) pasien. Kebanyakan pasien mempunyai frekuensi napas >20/menit pada 201 (94,3%) pasien, saturasi oksigen <90% pada 98 (46,0%) pasien, serta rontgen toraks: bronkopneumonia pada 134 (62,9%) pasien dan pneumonia pada 23 (10,7%) pasien. Komorbid adalah hipertensi, diabetes melitus, dan chronic heart failure pada 74 (34,7%), 56 (26,2%), dan 46 (11,7%) pasien berturut-turut. Lama rawat pasien yang meninggal 1–7 hari (22 pasien) dan 8–14 hari (9 pasien), berarti hampir semua pasien (29 dari 32) meninggal selama rawat 1–14 hari. Simpulan, mayoritas pasien COVID-19 di RSUD Cideres adalah wanita, berusia 41–60 tahun, keluhan saluran napas atas/napas pendek, GCS normal, rontgen toraks: bronkopneumonia dan pneumonia, komorbid: hipertensi, serta lama rawat pasien yang meninggal paling banyak 1–7 hari.
Background: The Cucumis sativus L has been used in traditional medicine for several conditions, with one of them being diabetes mellitus. The purpose of this experiment is to observe the anti-hyperglycemic effect of Cucumis sativus L on glucose absorption through the intestinal mucosal membrane of Wistar rats. Methods: The research was conducted on September-November 2012 at Biochemistry Laboratory, Faculty of Medicine, Universitas Padjadjaran. Using in situ perfusion method, the rat's epithelial mucosa in the intestine was bathed in a simple glucose solution in control, and bathed in glucose and Cucumis sativus L infusion in treatment. After admission, a sample was taken from the digestive tract and the glucose level was measured through a spectrophotometer. Result: There is no significant difference in the absorption of control and treatment solution. Conclusion: The Cucumis sativus L does not have any significant effect on the glucose absorption through the intestinal mucosal membrane. Further studies are still needed to reveal the antihyperglycemic mechanism of Cucumis sativus L.
Jumlah perokok aktif saat ini semakin meningkat sehingga perokok pasif dan residu yang tersisa atau paparan asap tersier juga meningkat. Salah satu dampak buruk rokok dapat menyebabkan dislipidemia, di antaranya peningkatan kadar kolesterol total dan trigliserida. Tujuan penelitian adalah menganalisis pengaruh paparan asap rokok tersier terhadap kadar kolesterol total dan trigliserida. Penelitian ini merupakan eksperimental in vivo dengan subjek penelitian mencit yang dibagi menjadi dua kelompok, yaitu kelompok kontrol yang tidak diberikan perlakuan dan kelompok perlakuan yang diberikan paparan asap rokok tersier selama 29 hari. Hasil penelitian menunjukkan bahwa tidak terdapat perbedaan kadar kolesterol dan trigliserida antara kelompok kontrol dan kelompok perlakuan (p>0,05). Hasil ini mengindikasikan bahwa paparan asap rokok tersier belum memengaruhi kadar kolesterol total dan trigliserida. Durasi paparan asap rokok akut dengan intensitas ringan yang diberikan pada penelitian ini diduga belum memengaruhi metabolisme lipid. EFFECT OF THIRDHAND SMOKE EXPOSURE ON TOTAL CHOLESTEROL AND TRIGLYCERIDE LEVEL IN MICENowadays, an increase in the number of active smokers also indicates an increase in passive smokers and residual smoke or thirdhand smoke exposure. One of the impact of cigarette is dyslipidemia, characterized by elevation level of total cholesterol and triglycerides. The objective of the study was to analyze the effect of thirdhand smoke exposure on the level of total cholesterol and triglycerides. This study used an in vivo experimental design with one cigarette a day and 20 mice as the subject. The subjects divided into 2 groups, the control group received no treatment and the treatment group received thirdhand smoke exposure for 29 days. The result of the study showed there was no significant difference in the level of total cholesterol and triglycerides among the control group and the treatment group (p>0.05). The result indicated that thirdhand smoke exposure had no effect on the level of total cholesterol and triglycerides. The duration of acute cigarette smoke exposure with low intensity given in this study suspected to not affect the lipid metabolism.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.