The biochemical effects of two compounds i.e. theophylline and furosemide were studied on the glassy clover snail Monacha obstructa. Animals were treated with sub-lethal concentration (¼ LC50) of each tested compound using contact (thin film) technique. Some biochemical parameters were measures at different periods after treatment. Results showed that the two tested compounds gradually reduced the activity of aspartate amino transferase (AST) and peroxidase enzymes with the prolongation of periods after treatment, while the contrary occurred with alanine aminotransferase (ALT) as both compounds enhanced its activity proportionally than control. Concerning lactic acid dehydrogenase (LDH), results showed severe reduction in its level after 1, 2, 3 and 4 days post-treatment. Also catalase enzyme took adverse way as its activity increased in the 1 st , 2 nd , 3 rd and 4 th days for both compounds. On the other hand, levels of the total protein and total lipid were significantly or insignificantly decreased post-treatment with the two tested compounds.
Background/aims Impairment of respiratory muscle function is common in patients with chronic kidney disease undergoing haemodialysis, and is manifested by decreased oxygenation and physical function. The purpose of this study was to analyse the impact of training with incentive spirometer on mobility of the diaphragm, arterial blood gases and functional capacity in patients with chronic kidney disease undergoing haemodialysis. Methods A pre–post research design was implemented. A total of 30 patients undergoing haemodialysis for chronic kidney disease received incentive spirometer training intradialysis three sessions a week for 8 weeks. Outcome measures were the amount of diaphragmatic mobility measured by ultrasonography, the levels of arterial partial pressure of oxygen, arterial partial pressure of carbon dioxide, oxygen saturation percentages and the distance walked in 6 minutes. Results Significant improvement from pre-treatment to post-treatment measurements occurred in all outcome measures, with P<0.05. Conclusions Incentive spirometer training should be recommended to be a part of daily routine of patients with chronic kidney disease who are undergoing haemodialysis to decrease respiratory and physical function impairments.
Introduction. Tobacco smoking is a major avoidable cause of morbidity. Smoking is one of the important factors which can alter normal lipid profile and it is among the major risk factors in the genesis of coronary atherosclerosis. The aim of this study was to determine the impact of high-intensity interval training on blood lipids and serum cotinine in Egyptian male smokers. Methods. overall, 30 sedentary male smokers with dyslipidaemia, with mean age of 30.16 ± 3.22 years, were enrolled in a highintensity interval training program calculated as 85-95% of their individualized maximum heart rate. The training program was applied for 30 minutes, 3 times per week for 8 weeks. Serum cotinine, low-density lipoprotein, high-density lipoprotein, triglycerides, and total cholesterol levels were measured before and after the intervention. Results. After the training program, a significant improvement (decrease) was observed in cotinine, low-density lipoprotein, triglycerides, and total cholesterol (by 39.94%, 7.13%, 5.09%, and 4.72%, respectively). Also, there was a significant improvement (increase) in high-density lipoprotein (by 17.07%). Conclusions. it is recommended for smokers to participate in high-intensity interval training to improve their lipid profile and decrease cotinine. These factors can play a role in reducing the risk for atherosclerosis.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.