■ We present the broad outlines of a roadmap toward human-level artificial general intelligence (henceforth, AGI). We begin by discussing AGI in general, adopting a pragmatic goal for its attainment and a necessary foundation of characteristics and requirements. An initial capability landscape will be presented, drawing on major themes from developmental psychology and illuminated by mathematical, physiological, and information-processing perspectives. The challenge of identifying appropriate tasks and environments for measuring AGI will be addressed, and seven scenarios will be presented as milestones suggesting a roadmap across the AGI landscape along with directions for future research and collaboration.This article is the result of an ongoing collaborative effort by the coauthors, preceding and during the AGI Roadmap Workshop held at the University of Of course, this is far from the first attempt to plot a course toward humanlevel AGI: arguably this was the goal of the founders of the field of artificial intelligence in the 1950s, and has been pursued by a steady stream of AI researchers since, even as the majority of the AI field has focused its attention on more narrow, specific subgoals. The ideas presented here build on the ideas of others in innumerable ways, but to review the history of AI

Astragalus membranaceus is an herbaceous perennial plant, growing to about 2 feet tall, with sprawling stems and alternate leaves about 12-24 leaflets. In total, 24 cross bred (Duroc × Landrace × Yorkshire) piglets weaned at 4 weeks with an average body weight of 10.84 ± 1.86 kg, were divided into four groups and randomly assigned to dietary treatments containing different AMSLF levels (0.00%, 2.50%, 5.00%, and 7.50%). The piglets in the control group (0.00% AMSLF) were fed basal diet and other treatment groups were fed basal diet in addition to 2.50%, 5.00%, and 7.50% pulverized AMSLF. The results indicated that supplementation with AMSLF significantly (p < 0.05) decreased diarrheal incidence in piglets. There was significant difference between treatment in terms of ADFI, ADG and FCR. Both 5.00% and 7.50% treatments significantly increased growth performance. The digestibility of gross energy and dry matter increased (p > 0.05) with increasing AMSLF level. The level of blood IL-2 and TNF-α were significantly affected by AMSLF supplementation with 7.50% AMSLF group having higher (p < 0.05) IL-2 and TNF-α levels than the other treatment groups. The 16SrDNA sequencing results from the four treatments showed that the potentially active bacterial microbial population and diversity in pig cecum were dominated by the phyla Bacteriodetes and Firmicutes regardless of the AMSLF supplementation. The Shannon diversity, PD whole tree diversity indices and Chao analyses exhibited significant variability in species richness across the treatments. The principal coordinates analysis (PCoA) showed significant (p < 0.1) differences between bacterial communities in all treatment groups. Results from the current study suggested that AMSLF supplementation increased composition of bacterial microbiota in pig gut. In conclusion, dietary supplements with AMSLF could potentially be used to prevent diarrheal incidence and improved pig production.

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Studies on dietary fiber and nutrient bioavailability have gained an increasing interest in both human and animal nutrition. Questions are increasingly being asked regarding the faith of nutrient components such as proteins, minerals, vitamins, and lipids after feed formulation. The aim of this review is to evaluate the evidence with the perspective of fiber usage in feed formulation. The consumption of dietary fiber may affect the absorption of nutrients in different ways. The physicochemical factors of dietary fiber, such as fermentation, bulking ability, binding ability, viscosity and gel formation, water-holding capacity and solubility affect nutrient absorption. The dietary fiber intake influences the different methods in which nutrients are absorbed. The increase in the total fiber content of the diet may delay the glycemic response. Soluble fiber decreased blood glucose content whereas purified insoluble fiber has a little or no effect on the blood glucose levels after a meal. Dietary fiber and prebiotics influence the host animal well-being by regulating blood glucose or insulin levels, stool bulking effects, increasing the acidity of the gut, constructive synthesis of short chain fatty acids (SCFAs), decreasing intestinal transit time, stimulating the growth of intestinal microbes, and increasing blood parameters. Previous studies suggest that fiber affects the bioavailability of nutrients, and maintains the host wellness.

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An experiment was conducted to determine the effects of including canola meal (CM) in nursery pig diets on growth performance, immune response, fecal microbial composition, and gut integrity. A total of 200 nursery pigs (initial body weight = 7.00 kg) were obtained in 2 batches of 100 pigs each. Pigs in each batch were housed in 25 pens (4 pigs/pen) and fed 5 diets in a randomized complete block design. The 5 diets were corn-soybean meal (SBM)-based basal diets with 0, 10, 20, 30, or 40% of CM. The diets were fed in 3 phases; Phase 1: d 0 to 7, Phase 2: d 7 to 21, and Phase 3: d 21 to 42. Diets in each phase were formulated to similar net energy, Ca, and digestible P and amino acid contents. Feed intake and body weight were measured by phase. Immune response and gut integrity parameters were measured for at the end of Phases 1 and 2. Fecal microbial composition for diets with 0 or 20% CM was determined at the end of Phase 2. Overall average daily gain (ADG) responded quadratically (P &lt; 0.05) to increasing dietary level of CM such that ADG was increased by 17% due to an increase in dietary level of CM from 0 to 20%, and was reduced by 16% due to an increase in dietary level of CM from 20 to 40%. Pigs fed diets with 0 or 40% CM did not differ in overall ADG. Dietary CM tended to quadratically decrease (P = 0.09) serum IgA level at the end of Phase 2 such that serum IgA level tended to reduce with an increase in dietary CM from 0 to 20%, and to increase with an increase in dietary CM from 20 to 40%. Dietary CM at 20% decreased (P &lt; 0.05) relative abundance of Bacteroidetes phylum and tended to increase (P = 0.07) relative abundance of Firmicutes phylum. Dietary CM linearly increased (P &lt; 0.05) the lactulose to mannitol ratio in the urine by 47 and 49% at the end of Phases 1 and 2, respectively; and tended to linearly decrease (P &lt; 0.10) ileal trans-epithelial electrical resistance at the end of Phase 1 by 64%. In conclusion, CM fed in the current study could be included in corn-SBM-based diets for nursery pigs 20% to improve growth performance and gut microbial composition, and reduce immune response. Also, the CM used in the current study could be included in corn-SBM-based diets for nursery pigs at 30 or 40% without compromising growth performance. Dietary CM increased gut permeability, implying that dietary CM at 20% improves growth performance of weaned pigs through mechanisms other than reducing gut permeability.

BACKGROUND Pleurotus ostreatus mushroom (POM) is an edible mushroom with rich nutritional components and vital pharmacological properties. The present study comprised 100 cross‐bred piglets, weaned at 28 days old, who were randomly assigned to four POM diets with five replicates per diet and five piglets per pen. RESULTS POM supplementation ( P < 0.05) decreased the incidence of diarrhea, and also increased the average daily feed intake and average daily gain of pigs. Fecal acetate, butyrate and propionate increased with the addition of POM. Interleukin‐2, immunoglobulin G, immunoglobulin M, tumor necrosis factor‐α and immunoglobulin A increased ( P < 0.05) with the addition of POM. The 16S rDNA sequencing results showed that the Bacteroidetes and Firmicutes were the dominant microbial strains in the fecal samples, irrespective of POM supplementation. Shannon diversity, whole tree phylogenetic diversity, observed species and Chao1 analysis exhibited significant variation in species richness across the treatments. Principal coordinates analysis showed a significant ( P < 0.1) increase in the microbial communities amongst all of the treatment groups. CONCLUSION The results of the present study suggest that the supplementation of POM in the diet of piglets might increase feed consumption, gut microbial composition and diversity, as well as short‐chain fatty acids synthesis, consequently preventing the occurrence of diarrhea and increasing the growth of piglets. © 2019 The Authors. Journal of The Science of Food and Agriculture published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.

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